Histone modification regulates replication-coupled nucleosome assembly, DNA damage
repair, and gene transcription. Changes or mutations in factors involved in nucleosome …

Advances in structural analysis by cryogenic electron microscopy (cryo-EM) and X-ray
crystallography have revealed the tertiary structures of various chromatin-related proteins …

Linker histone H1 plays a crucial role in various biological processes, including nucleosome
stabilization, high-order chromatin structure organization, gene expression, and epigenetic …

Background: Betel nut/areca nut/Areca catechu is one of the most commonly used
psychoactive substance, and is also a major preventable cause of cancer. Unlike other …

The cytochromes P450 (CYPs) represent a large gene superfamily that plays an important
role in the metabolism of both exogenous and endogenous compounds. We have reported …

The NLR family pyrin domain containing 3 (NLRP3) inflammasome is involved in the innate
immune system and is a three-part macromolecular complex comprising the NLRP3 protein …

All cellular processes that involve the unwinding of DNA also lead to the systematic shuttling
of histones. Histone shuttling across the nuclear membrane is facilitated by a class of …

Introduction Molecular chaperones and co-chaperones are highly conserved cellular
components that perform a variety of duties related to the proper three-dimensional folding …

The nucleosome is composed of histones and DNA. Prior to their deposition on chromatin,
histones are shielded by specialized and diverse proteins known as histone chaperones …

Molecular chaperones and co-chaperones are highly conserved cellular components that
perform variety of duties related to the proper three-dimensional folding of the proteome. The …