Activity has an important role in refining synaptic connectivity during development, in part
through'Hebbian'mechanisms such as long-term potentiation and long-term depression …

Neuronal circuits in the brain are shaped by experience during'critical periods' in early
postnatal life. In the primary visual cortex, this activity-dependent development is triggered …

A growing number of research publications have illustrated the remarkable ability of the
brain to reorganize itself in response to various sensory experiences. A traditional view of …

▪ Abstract It has been clear for almost two decades that cortical representations in adult
animals are not fixed entities, but rather, are dynamic and are continuously modified by …

SYNCHRONIZATION of neuronal activity is fundamental in the operation of cortical
networks1. With respect to an ongoing synchronized oscillation, the precise timing of action …

We report that variations in maternal care in the rat promote hippocampal synaptogenesis
and spatial learning and memory through systems known to mediate experience-dependent …

Sensory experience and learning alter sensory representations in cerebral cortex. The
synaptic mechanisms underlying sensory cortical plasticity have long been sought. Recent …

A lifecourse perspective is key for understanding and interpreting racial and ethnic patterns
in neuropsychological test performance. In this article, we discuss contextual factors that …

The mechanisms underlying experience-dependent plasticity and refinement of central
circuits are not yet fully understood. A non-Hebbian form of synaptic plasticity, which scales …

Experience-dependent plasticity in somatosensory (S1) and visual (V1) cortex involves rapid
depression of responses to a deprived sensory input (a closed eye or a trimmed whisker) …