Revisiting the rules of life for viruses of microorganisms

AMS Correa, C Howard-Varona, SR Coy… - Nature Reviews …, 2021 - nature.com
Viruses that infect microbial hosts have traditionally been studied in laboratory settings with
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …

Fast and flexible multiagent decision-making

NE Leonard, A Bizyaeva, A Franci - Annual Review of Control …, 2024 - annualreviews.org
A multiagent system should be capable of fast and flexible decision-making to successfully
manage the uncertainty, variability, and dynamic change encountered when operating in the …

Communication between viruses guides lysis–lysogeny decisions

Z Erez, I Steinberger-Levy, M Shamir, S Doron… - Nature, 2017 - nature.com
Temperate viruses can become dormant in their host cells, a process called lysogeny. In
every infection, such viruses decide between the lytic and the lysogenic cycles, that is …

Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection

B Wang, AE Lin, J Yuan, KE Novak, MD Koch… - Nature …, 2023 - nature.com
Bacterial populations are highly adaptive. They can respond to stress and survive in shifting
environments. How the behaviours of individual bacteria vary during stress, however, is …

Contemporary phage biology: from classic models to new insights

G Ofir, R Sorek - Cell, 2018 - cell.com
Bacteriophages, discovered about a century ago, have been pivotal as models for
understanding the fundamental principles of molecular biology. While interest in phage …

Bacteriophages and their potential for treatment of gastrointestinal diseases

Y Duan, R Young, B Schnabl - Nature reviews Gastroenterology & …, 2022 - nature.com
Although bacteriophages have been overshadowed as therapeutic agents by antibiotics for
decades, the emergence of multidrug-resistant bacteria and a better understanding of the …

Dynamic biofilm architecture confers individual and collective mechanisms of viral protection

L Vidakovic, PK Singh, R Hartmann, CD Nadell… - Nature …, 2018 - nature.com
In nature, bacteria primarily live in surface-attached, multicellular communities, termed
biofilms,,,,–. In medical settings, biofilms cause devastating damage during chronic and …

Embracing the enemy: the diversification of microbial gene repertoires by phage-mediated horizontal gene transfer

M Touchon, JAM De Sousa, EPC Rocha - Current opinion in microbiology, 2017 - Elsevier
Highlights•Phages drive horizontal gene transfer between prokaryotes.•Lysogenic
conversion provides novel adaptive traits, at the cost of eventual lysis.•Prophages account …

[HTML][HTML] Cellular decision making and biological noise: from microbes to mammals

G Balázsi, A Van Oudenaarden, JJ Collins - Cell, 2011 - cell.com
Cellular decision making is the process whereby cells assume different, functionally
important and heritable fates without an associated genetic or environmental difference …

Challenges in measuring and understanding biological noise

N Eling, MD Morgan, JC Marioni - Nature Reviews Genetics, 2019 - nature.com
Biochemical reactions are intrinsically stochastic, leading to variation in the production of
mRNAs and proteins within cells. In the scientific literature, this source of variation is typically …