Tonotopic reorganization of developing auditory brainstem circuits

K Kandler, A Clause, J Noh - Nature neuroscience, 2009 - nature.com
A fundamental organizing principle of auditory brain circuits is tonotopy, the orderly
representation of the sound frequency to which neurons are most sensitive. Tonotopy arises …

The auditory hair cell ribbon synapse: from assembly to function

S Safieddine, A El-Amraoui… - Annual review of …, 2012 - annualreviews.org
Cochlear inner hair cells (IHCs), the mammalian auditory sensory cells, encode acoustic
signals with high fidelity by Graded variations of their membrane potential trigger rapid and …

Music training improves pitch perception in prelingually deafened children with cochlear implants

JKC Chen, AYC Chuang, C McMahon, JC Hsieh… - …, 2010 - publications.aap.org
OBJECTIVE: The comparatively poor music appreciation in patients with cochlear implants
might be ascribed to an inadequate exposure to music; however, the effect of training on …

Development of tonotopy in the auditory periphery

ZF Mann, MW Kelley - Hearing research, 2011 - Elsevier
Acoustic frequency analysis plays an essential role in sound perception, communication and
behavior. The auditory systems of most vertebrates that perceive sounds in air are organized …

Between molecules and experience: role of early patterns of coordinated activity for the development of cortical maps and sensory abilities

IL Hanganu-Opatz - Brain research reviews, 2010 - Elsevier
Sensory systems processing information from the environment rely on precisely formed and
refined neuronal networks that build maps of sensory receptor epithelia at different …

Morphological and physiological development of auditory synapses

WM Yu, LV Goodrich - Hearing research, 2014 - Elsevier
Acoustic communication requires gathering, transforming, and interpreting diverse sound
cues. To achieve this, all the spatial and temporal features of complex sound stimuli must be …

Otic mesenchyme cells regulate spiral ganglion axon fasciculation through a Pou3f4/EphA4 signaling pathway

TM Coate, S Raft, X Zhao, AK Ryan, EB Crenshaw… - Neuron, 2012 - cell.com
Peripheral axons from auditory spiral ganglion neurons (SGNs) form an elaborate series of
radially and spirally oriented projections that interpret complex aspects of the auditory …

Making connections in the inner ear: recent insights into the development of spiral ganglion neurons and their connectivity with sensory hair cells

TM Coate, MW Kelley - Seminars in cell & developmental biology, 2013 - Elsevier
In mammals, auditory information is processed by the hair cells (HCs) located in the cochlea
and then rapidly transmitted to the CNS via a specialized cluster of bipolar afferent …

Synaptic refinement of an inhibitory topographic map in the auditory brainstem requires functional Cav1. 3 calcium channels

JJ Hirtz, N Braun, D Griesemer, C Hannes… - Journal of …, 2012 - Soc Neuroscience
Synaptic refinement via the elimination of inappropriate synapses and strengthening of
appropriate ones is crucially important for the establishment of specific, topographic neural …

Towards the identification of a genetic basis for L andau‐K leffner s yndrome

J Conroy, PA McGettigan, D McCreary, N Shah… - …, 2014 - Wiley Online Library
Objective To establish the genetic basis of L andau‐K leffner syndrome (LKS) in a cohort of
two discordant monozygotic (MZ) twin pairs and 11 isolated cases. Methods We used a …