Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications

F Zhang, RI Lau, Q Liu, Q Su, FKL Chan… - Nature Reviews …, 2023 - nature.com
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

W Ni, X Yang, D Yang, J Bao, R Li, Y Xiao, C Hou… - Critical Care, 2020 - Springer
An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global …

[HTML][HTML] Serotonin reduction in post-acute sequelae of viral infection

AC Wong, AS Devason, IC Umana, TO Cox… - Cell, 2023 - cell.com
Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …

[HTML][HTML] Alterations in gut microbiota of patients with COVID-19 during time of hospitalization

T Zuo, F Zhang, GCY Lui, YK Yeoh, AYL Li, H Zhan… - Gastroenterology, 2020 - Elsevier
Background & Aims Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) infects gastrointestinal tissues, little is known about the roles of gut commensal microbes …

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

AR Bourgonje, AE Abdulle, W Timens… - The Journal of …, 2020 - Wiley Online Library
Abstract Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional
host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan

X Li, S Xu, M Yu, K Wang, Y Tao, Y Zhou, J Shi… - Journal of Allergy and …, 2020 - Elsevier
Background In December 2019, the coronavirus disease 2019 (COVID-19) outbreak
occurred in Wuhan. Data on the clinical characteristics and outcomes of patients with severe …

Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2

M Gheblawi, K Wang, A Viveiros, Q Nguyen… - Circulation …, 2020 - Am Heart Assoc
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …

Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

M Guo, W Tao, RA Flavell, S Zhu - Nature reviews Gastroenterology & …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …

Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from a Hong Kong cohort: systematic review and meta-analysis

KS Cheung, IFN Hung, PPY Chan, KC Lung, E Tso… - Gastroenterology, 2020 - Elsevier
Background & Aims Infection with severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) causes coronavirus disease 2019 (COVID-19), which has been characterized by …

Impact of bacterial metabolites on gut barrier function and host immunity: a focus on bacterial metabolism and its relevance for intestinal inflammation

N Gasaly, P De Vos, MA Hermoso - Frontiers in immunology, 2021 - frontiersin.org
The diverse and dynamic microbial community of the human gastrointestinal tract plays a
vital role in health, with gut microbiota supporting the development and function of the gut …