Molecular effects of exercise training in patients with cardiovascular disease: focus on skeletal muscle, endothelium, and myocardium

V Adams, B Reich, M Uhlemann… - American Journal of …, 2017 - journals.physiology.org
For decades, we have known that exercise training exerts beneficial effects on the human
body, and clear evidence is available that a higher fitness level is associated with a lower …

[HTML][HTML] 0.9% saline is neither normal nor physiological

H Li, S Sun, JQ Yap, J Chen, Q Qian - Journal of Zhejiang …, 2016 - ncbi.nlm.nih.gov
The purpose of this review is to objectively evaluate the biochemical and pathophysiological
properties of 0.9% saline (henceforth: saline) and to discuss the impact of saline infusion …

Pathophysiological roles of peroxynitrite in circulatory shock

C Szabó, K Módis - Shock, 2010 - journals.lww.com
Peroxynitrite is a reactive oxidant produced from nitric oxide and superoxide, which reacts
with proteins, lipids, and DNA, and promotes cytotoxic and proinflammatory responses …

[HTML][HTML] Cerulein pancreatitis: oxidative stress, inflammation, and apoptosis

H Kim - Gut and liver, 2008 - ncbi.nlm.nih.gov
Cerulein pancreatitis is similar to human edematous pancreatitis, manifesting with
dysregulation of digestive enzyme production and cytoplasmic vacuolization, the death of …

Chronic endurance exercise induces quadriceps nitrosative stress in patients with severe COPD

E Barreiro, R Rabinovich, J Marin-Corral, JA Barbera… - Thorax, 2009 - thorax.bmj.com
Background: Although exercise training has beneficial effects on skeletal muscle
bioenergetics and exercise performance in patients with severe chronic obstructive …

Pterostilbene protects against myocardial ischemia/reperfusion injury via suppressing oxidative/nitrative stress and inflammatory response

Z Yu, S Wang, X Zhang, Y Li, Q Zhao, T Liu - International …, 2017 - Elsevier
Recent studies have shown that pterostilbene (Pte) confers protection against myocardial
ischemia/reperfusion injury. The oxidative/nitrative stress and inflammation induce injury …

[HTML][HTML] Recent insights into muscle fatigue at the cross-bridge level

EP Debold - Frontiers in physiology, 2012 - frontiersin.org
The depression in force and/or velocity associated with muscular fatigue can be the result of
a failure at any level, from the initial events in the motor cortex of the brain to the formation of …

[HTML][HTML] Direct regulation of striated muscle myosins by nitric oxide and endogenous nitrosothiols

AM Evangelista, VS Rao, AR Filo, NV Marozkina… - PloS one, 2010 - journals.plos.org
Background Nitric oxide (NO) has long been recognized to affect muscle contraction, both
through activation of guanylyl cyclase and through modification of cysteines in proteins to …

Recent insights into the molecular basis of muscular fatigue.

EP Debold - Medicine and science in sports and exercise, 2012 - europepmc.org
The cause of muscle fatigue has been studied for more than 100 yr, yet its molecular basis
remains poorly understood. Prevailing theories suggest that much of the fatigue-induced …

Molecular mechanisms of mechanical function changes of the rat myocardium under subchronic lead exposure

OP Gerzen, SR Nabiev, SV Klinova… - Food and Chemical …, 2022 - Elsevier
A moderate degree of lead intoxication was observed in male rats after repeated
intraperitoneal injections with two doses of lead acetate three times a week during 5 (12.5 …