Monoterpenes and their derivatives—Recent development in biological and medical applications

M Zielińska-Błajet, J Feder-Kubis - International Journal of Molecular …, 2020 - mdpi.com
Monoterpenes, comprising hydrocarbons, are the largest class of plant secondary
metabolites and are commonly found in essential oils. Monoterpenes and their derivatives …

Mono-and sesquiterpenes as a starting platform for the development of antiviral drugs

OI Yarovaya, NF Salakhutdinov - Russian Chemical Reviews, 2021 - iopscience.iop.org
The revies focuses on low-molecular-weight plant metabolites (mono-and sesquiterpenes)
exhibiting antiviral activity. Data on antiviral action of both essential oils and plant extracts …

Borneol ester derivatives as entry inhibitors of a wide spectrum of SARS-CoV-2 viruses

OI Yarovaya, DN Shcherbakov, SS Borisevich… - Viruses, 2022 - mdpi.com
In the present work we studied the antiviral activity of the home library of monoterpenoid
derivatives using the pseudoviral systems of our development, which have glycoproteins of …

Nanomaterial-based drug delivery systems as promising carriers for patients with COVID-19

M Abd Elkodous, SO Olojede, M Morsi, GS El-Sayyad - RSC advances, 2021 - pubs.rsc.org
Once the World Health Organization (WHO) declared the COVID-19 outbreak to be
pandemic, massive efforts have been launched by researchers around the globe to combat …

Molecular Modeling of Viral Type I Fusion Proteins: Inhibitors of Influenza Virus Hemagglutinin and the Spike Protein of Coronavirus

SS Borisevich, VV Zarubaev, DN Shcherbakov… - Viruses, 2023 - mdpi.com
The fusion of viral and cell membranes is one of the basic processes in the life cycles of
viruses. A number of enveloped viruses confer fusion of the viral envelope and the cell …

Essential oils and their compounds as potential anti-influenza agents

AO Oriola, AO Oyedeji - Molecules, 2022 - mdpi.com
Essential oils (EOs) are chemical substances, mostly produced by aromatic plants in
response to stress, that have a history of medicinal use for many diseases. In the last few …

Bioprospecting phytochemicals of Rosmarinus officinalis L. for targeting SARS-CoV-2 main protease (Mpro): a computational study

U Patel, K Desai, RC Dabhi, JJ Maru… - Journal of Molecular …, 2023 - Springer
Context The persistent spread of highly contagious COVID-19 disease is one of the
deadliest occurrences in the history of mankind. Despite the distribution of numerous …

Discovery of new ginsenol-like compounds with high antiviral activity

AS Volobueva, OI Yarovaya, MV Kireeva… - Molecules, 2021 - mdpi.com
A number of framework amides with a ginsenol backbone have been synthesized using the
Ritter reaction. We named the acetamide as Ginsamide. A method was developed for the …

Synthesis of camphecene and cytisine conjugates using click chemistry methodology and study of their antiviral activity

OI Artyushin, AA Moiseeva, VV Zarubaev… - Chemistry & …, 2019 - Wiley Online Library
A series of camphecene and quinolizidine alkaloid (−)‐cytisine conjugates has been
obtained for the first time using 'click'chemistry methodology. The cytotoxicity and virus …

Synthesis and antiviral activity of novel imidazo[2,1‐b]thiazoles coupled with morpholine and thiomorpholines

N Chirra, V Shanigarapu, NP Abburi… - Journal of …, 2024 - Wiley Online Library
Herein described the synthesis and antiviral evaluation of a novel series of morpholine and
thio‐morpholine coupled imidazo [2, 1‐b] thiazoles. The three‐step reaction sequence …