A-to-I editing of coding and non-coding RNAs by ADARs

K Nishikura - Nature reviews Molecular cell biology, 2016 - nature.com
Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-
stranded RNA. This A-to-I editing occurs not only in protein-coding regions of mRNAs, but …

RNA editing in the forefront of epitranscriptomics and human health

T Christofi, A Zaravinos - Journal of translational medicine, 2019 - Springer
Post-transcriptional modifications have been recently expanded with the addition of RNA
editing, which is predominantly mediated by adenosine and cytidine deaminases acting on …

Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase

JB Patterson, CE Samuel - Molecular and cellular biology, 1995 - Taylor & Francis
A 6,474-nucleotide human cDNA clone designated K88, which encodes double-stranded
RNA (dsRNA)-specific adenosine deaminase, was isolated in a screen for interferon (IFN) …

[HTML][HTML] Expression and intracellular localization of mouse Vasa-homologue protein during germ cell development

Y Toyooka, N Tsunekawa, Y Takahashi… - Mechanisms of …, 2000 - Elsevier
To demonstrate the cellular and subcellular localization of mouse vasa homologue protein
during germ cell development, specific antibody was raised against the full-length MVH …

Exploring the epitranscriptome by native RNA sequencing

O Begik, JS Mattick, EM Novoa - RNA, 2022 - rnajournal.cshlp.org
Chemical RNA modifications, collectively referred to as the “epitranscriptome,” are essential
players in fine-tuning gene expression. Our ability to analyze RNA modifications has …

Adenosine deaminase that acts on RNA 3 (ADAR3) binding to glutamate receptor subunit B pre-mRNA inhibits RNA editing in glioblastoma

E Oakes, A Anderson, A Cohen-Gadol… - Journal of Biological …, 2017 - ASBMB
RNA editing is a cellular process that precisely alters nucleotide sequences, thus regulating
gene expression and generating protein diversity. Over 60% of human transcripts undergo …

The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis

JE Shima, DJ McLean, JR McCarrey… - Biology of …, 2004 - academic.oup.com
One of the most promising applications of microarrays is the study of changes in gene
expression associated with the growth and development of mammalian tissues. The testis …

Molecular mechanisms of male germ cell differentiation

NB Hecht - Bioessays, 1998 - Wiley Online Library
During spermatogenesis, diploid stem cells differentiate, undergo meiosis, and transform
into haploid spermatozoa. As this precisely timed series of events proceeds, chromosomal …

The dsRNA binding protein family: critical roles, diverse cellular functions

LR Saunders, GN Barber - The FASEB Journal, 2003 - Wiley Online Library
The dsRNA binding proteins (DRBPs) comprise a growing family of eukaryotic, prokaryotic,
and viral‐encoded products that share a common evolutionarily conserved motif specifically …

[图书][B] DNA and RNA modification enzymes: structure, mechanism, function and evolution

H Grosjean - 2009 - taylorfrancis.com
This volume is a timely and comprehensive description of the many facets of DNA and RNA
modification-editing processes and to some extent repair mechanisms. Each chapter offers …