T Christofi, A Zaravinos - Journal of translational medicine, 2019 - Springer
Post-transcriptional modifications have been recently expanded with the addition of RNA editing, which is predominantly mediated by adenosine and cytidine deaminases acting on …
JB Patterson, CE Samuel - Molecular and cellular biology, 1995 - Taylor & Francis
A 6,474-nucleotide human cDNA clone designated K88, which encodes double-stranded RNA (dsRNA)-specific adenosine deaminase, was isolated in a screen for interferon (IFN) …
Y Toyooka, N Tsunekawa, Y Takahashi… - Mechanisms of …, 2000 - Elsevier
To demonstrate the cellular and subcellular localization of mouse vasa homologue protein during germ cell development, specific antibody was raised against the full-length MVH …
Chemical RNA modifications, collectively referred to as the “epitranscriptome,” are essential players in fine-tuning gene expression. Our ability to analyze RNA modifications has …
RNA editing is a cellular process that precisely alters nucleotide sequences, thus regulating gene expression and generating protein diversity. Over 60% of human transcripts undergo …
JE Shima, DJ McLean, JR McCarrey… - Biology of …, 2004 - academic.oup.com
One of the most promising applications of microarrays is the study of changes in gene expression associated with the growth and development of mammalian tissues. The testis …
During spermatogenesis, diploid stem cells differentiate, undergo meiosis, and transform into haploid spermatozoa. As this precisely timed series of events proceeds, chromosomal …
LR Saunders, GN Barber - The FASEB Journal, 2003 - Wiley Online Library
The dsRNA binding proteins (DRBPs) comprise a growing family of eukaryotic, prokaryotic, and viral‐encoded products that share a common evolutionarily conserved motif specifically …
This volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers …