J. Neurochem.(2012) 120, 948–963. Abstract Microglia are the resident immune cells within
the brain and their production of immune molecules such as cytokines and chemokines is …

Because fetal brain development proceeds at an extremely rapid pace, early life
experiences have the potential to alter the trajectory of neurodevelopment, which may …

Alzheimer's disease, the most common form of dementia, was first formally described in
1907 yet its etiology has remained elusive. Recent proposals that Aβ peptide may be part of …

While recent advances in diagnostics and therapeutics offer promising new approaches for
Alzheimer's disease (AD) diagnosis and treatment, there is still an unmet need for an …

Exposure to inflammation during pregnancy has been linked to adverse
neurodevelopmental consequences for the offspring. One common route through which a …

Maternal systemic inflammation increases risk for neurodevelopmental disorders like autism,
ADHD, and schizophrenia in offspring. Notably, these disorders are male-biased. Studies …

Background Studies on the gender-specific effect of PrA on children's emotional and
behavioral development are limited. Lack of PrA data on the entire pregnancy had caused …

Neonatal exposure of rodents to an immune challenge alters a variety of behavioural and
physiological parameters in adulthood. In particular, neonatal lipopolysaccharide (LPS; 0.05 …

Hypoxia–ischemia on 3-day-old rats (HIP3) allows the investigation of HI damage in the
immature brain. HIP3 is characterized for neurological disabilities caused by white matter …

Background Olfactory impairments are prominent in both schizophrenia and the preceding
at-risk state. Their presence prior to illness predicts poor functional outcome. In …