α-Glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis

FA Van de Laar, PL Lucassen, RP Akkermans… - Diabetes …, 2005 - Am Diabetes Assoc
OBJECTIVE—To review the effects of monotherapy with α-glucosidase inhibitors (AGIs) for
patients with type 2 diabetes, with respect to mortality, morbidity, glycemic control, insulin …

Alpha‐glucosidase inhibitors for type 2 diabetes mellitus

FA Van de Laar, PLBJ Lucassen… - Cochrane database …, 2005 - cochranelibrary.com
Background Alpha‐glucosidase inhibitors such as acarbose or miglitol, have the potential to
improve glycemic control in type 2 diabetes mellitus. The true value of these agents …

α‐Glucosidase inhibitors

R Rabasa‐Lhoret, JL Chiasson - International textbook of …, 2003 - Wiley Online Library
Abstract α‐Glucosidase inhibitors produce a significant reduction of postprandial
hyperglycemia and postprandial insulin with a significant decrease of HbA1c (∼ 0.7%), by …

The effect of acarbose on lipid profiles in adults: a systematic review and meta-analysis of randomized clinical trials

M Yousefi, ST Fateh, M Nikbaf-Shandiz… - BMC Pharmacology and …, 2023 - Springer
Purpose Dyslipidemia, characterized by elevated levels of triglycerides (TG), low-density
lipoprotein (LDL), total cholesterol (TC), and reduced levels of high-density lipoprotein …

The effects of acarbose treatment on cardiovascular risk factors in impaired glucose tolerance and diabetic patients: a systematic review and dose–response meta …

M Zamani, M Nikbaf-Shandiz, Y Aali, N Rasaei… - Frontiers in …, 2023 - frontiersin.org
Acarbose (ACB) seems to be an effective drug in the management of cardiovascular risk
factors. However, no previous meta-analysis of randomized controlled trials (RCTs) has …

Who should benefit from the use of alpha-glucosidase inhibitors?

A Godbout, JL Chiasson - Current diabetes reports, 2007 - Springer
Although most commonly used drugs such as biguanides, sulfonylureas, and more recently,
thiazolidinediones, are effective in controlling fasting hyperglycemia, a high percentage of …

Predictors of persistence of use of the novel antidiabetic agent acarbose

VS Catalan, JA Couture, J LeLorier - Archives of internal …, 2001 - jamanetwork.com
Background A carbose is the first of a new class of antidiabetic agents, the α-glucosidase
inhibitors. This study characterizes and identifies predictors of persistence of use of …

Biosynthesis of unusual aminocyclitol-containing natural products

T Mahmud, PM Flatt, X Wu - Journal of natural products, 2007 - ACS Publications
The aminocyclitol family of natural products is a class of sugar-derived microbial secondary
metabolites that demonstrate significant biological activities. Within this class of natural …

α‐Glucosidase inhibitors

J Leroux‐Stewart, R Rabasa‐Lhoret… - … textbook of diabetes …, 2015 - Wiley Online Library
Alpha‐glucosidase inhibitors are oral antidiabetic medications that delay the digestion of
complex carbohydrates by acting as competitive inhibitors of intestinal α‐glucosidases. By …

Efficacy and tolerability of acarbose in Asian patients with type 2 diabetes inadequately controlled with diet and sulfonylureas

BJ Lin, HP Wu, HS Huang, J Huarng, A Sison… - Journal of Diabetes and …, 2003 - Elsevier
The objective of this study was to investigate the efficacy, tolerability, and safety of acarbose
in the improvement of glycemic control in Asian patients with type 2 diabetes inadequately …