The increasing incidence of apoptosis resistance have indicated that ferroptosis, a novel cell
death pathway, is deeply associated with the proliferation and survival of cancer cells. This …

The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) represents the
master regulator of the cellular antioxidant response and plays a critical role in …

Photothermal therapy (PTT) utilizes near-infrared (NIR) light to enhance localized, non-
invasive cancer treatments and drug delivery systems (DDS). Combination chemotherapy …

Triple negative breast cancer (TNBC) stands out as an aggressive and lethal subtype of
breast cancer. Despite being a mainstay in treatment, the efficacy of paclitaxel (PTX) …

Colorectal cancer is a lethal malignancy that begins from acquired/inherent premalignant
lesions. Thus, targeting these lesions at an early stage of the disease could impede the …

Nanocarriers responding to tumor microenvironment have been extensively exploited to
improve the antitumor outcome of chemotherapeutic drugs. However, selectively and …

Whey proteins (WPs) are the most actively flourishing class of pharmaceutically active
compounds. WPs have high biological value and are dominated by crucial components …

The clinical advancement of protein-based nanomedicine has revolutionized medical
professionals' perspectives on cancer therapy. Protein-based nanoparticles have been …

Apremilast (APR) is a potent anti-psoriatic agent that inhibits the phosphodiesterase 4
enzyme. Due to the poor oral bioavailability and associated systemic side effects the clinical …

Bcl-2 protein plays an integral role in hijacking apoptosis and triggering chemoresistance in
triple negative breast cancer (TNBC). The present study explored the therapeutic efficacy of …