The ability to regenerate extensive portions of the body is widespread among the phylum
Annelida and this group includes some of the most highly regenerative animals known …

Recent studies demonstrated that allograft inflammatory factor-1 (AIF-1) and RNASET2 act
as chemoattractants for macrophages and modulate the inflammatory processes in both …

The annelids are an excellent group in which to investigate the evolution of regeneration
abilities. They exhibit qualitative and quantitative variation in regeneration ability, including …

Many animals can regenerate, although there is great diversity in regenerative capabilities.
A major question in regenerative biology is determining the cellular source of newly formed …

Several studies have recently demonstrated that the correct regeneration of damaged
tissues and the maintaining of homeostasis after wounds or injuries are tightly connected to …

Cells involved in leech inflammatory responses have been characterized by morphological,
histochemical, and immunohistochemical methods. Macrophage-like cells, NK-like cells …

The innate immune response is the first line of defence strategies in invertebrates against
attack of infectious agents. A detailed analysis of the immune mechanisms involved in …

Basic studies on angiogenesis in normal and pathologic conditions, as well as research on
drugs or genes/proteins that stimulate or regulate the angiogenic process, can rely on an …

We focused our studies on the leech, Hirudo medicinalis. This invertebrate has a relative
anatomical simplicity and is a reliable model for studying a variety of basic events, such as …

Adult skeletal muscle in vertebrates contains myoendothelial cells that express both
myogenic and endothelial markers, and which are able to differentiate into myogenic cells to …