Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children< 5
years of age. Despite the global introduction of vaccinations for rotavirus over a decade ago …

Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

RNA viruses face dynamic environments and are masters at adaptation. During their
short'lifespans', they must surmount multiple physical, anatomical and immunological …

Heat shock protein 70 (Hsp70a) is a molecular chaperone that is expressed in response to
stress. In this role, Hsp70 binds to its protein substrates and stabilize them against …

Heat shock proteins (HSPs) are constitutively expressed under physiological conditions in
most organisms but their expression can significantly enhance in response to four types of …

As intracellular parasites, viruses rely heavily on the use of numerous cellular machineries
for completion of their replication cycle. The recent discovery of the heterogeneous …

Dengue virus requires the presence of an unidentified cellular receptor on the surface of the
host cell. By using a recently published affinity chromatography approach, an 84-kDa …

Rotavirus (RV) is the foremost enteric pathogen associated with severe diarrheal illness in
young children (< 5years) and animals worldwide. RV primarily infects mature enterocytes in …

Direct‐acting antiviral agents (DAAs) represent a class of drugs targeting viral proteins and
have been demonstrated to be very successful in combating viral infections in clinic …