Spray drying of pharmaceuticals and biopharmaceuticals: Critical parameters and experimental process optimization approaches

A Ziaee, AB Albadarin, L Padrela, T Femmer… - European Journal of …, 2019 - Elsevier
Spray drying is increasingly becoming recognized as an efficient drying and formulation
technique for pharmaceutical and biopharmaceutical processing. It offers significant …

Physical stability of dry powder inhaler formulations

N Shetty, D Cipolla, H Park, QT Zhou - Expert opinion on drug …, 2020 - Taylor & Francis
ABSTRACT Introduction: Dry powder inhalers (DPIs) are popular for pulmonary drug
delivery. Various techniques have been employed to produce inhalation drug particles and …

[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties

N Alhajj, NJ O'Reilly, H Cathcart - Powder Technology, 2021 - Elsevier
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …

Inhalation delivery for the treatment and prevention of COVID-19 infection

BB Eedara, W Alabsi, D Encinas-Basurto, R Polt… - Pharmaceutics, 2021 - mdpi.com
Coronavirus disease-2019 (COVID-19) is caused by coronavirus-2 (SARS-CoV-2) and has
produced a global pandemic. As of 22 June 2021, 178 million people have been affected …

The wound healing and antibacterial potential of triple-component nanocomposite (chitosan-silver-sericin) films loaded with moxifloxacin

A Shah, MA Buabeid, ESA Arafa, I Hussain, L Li… - International Journal of …, 2019 - Elsevier
Aim The current study reports the development and evaluation of chitosan-sericin-silver
nanocomposite (CSSN) films without and with moxifloxacin (Mox). Methodology The film …

On the particle formation of leucine in spray drying of inhalable microparticles

M Ordoubadi, FKA Gregson, H Wang… - International journal of …, 2021 - Elsevier
The particle formation of L-leucine, a dispersibility-enhancing amino acid used in the spray
drying of inhalable pharmaceutical aerosols, was extensively studied using three …

Spray-dried inhalable powder formulations of therapeutic proteins and peptides

BB Eedara, W Alabsi, D Encinas-Basurto, R Polt… - AAPS …, 2021 - Springer
Respiratory diseases are among the leading causes of morbidity and mortality worldwide.
Innovations in biochemical engineering and understanding of the pathophysiology of …

Rifabutin loaded inhalable β-glucan microparticle based drug delivery system for pulmonary TB

F Ahmad, S Ahmad, TK Upadhyay, S Singh… - Scientific Reports, 2024 - nature.com
Inhalable microparticle-based anti TB drug delivery systems are being investigated
extensively for Tuberculosis [TB] treatment as they offer efficient and deep lung deposition …

Gellan gum-based bilayer mucoadhesive films loaded with moxifloxacin hydrochloride and clove oil for possible treatment of periodontitis

A Li, IN Khan, IU Khan, AM Yousaf… - Drug design …, 2021 - Taylor & Francis
Background/Objective Periodontitis is a widely spread oral infection and various antibiotics
are utilized for its treatment, but high oral doses and development of antibiotic resistance …

Synthesis, in vitro characterization and antibacterial efficacy of moxifloxacin-loaded chitosan-pullulan-silver-nanocomposite films

A Shah, AA Ashames, MA Buabeid… - Journal of Drug Delivery …, 2020 - Elsevier
Current study reports the facile synthesis, in-vitro characterization and antibacterial efficacy
of novel moxifloxacin (Mox)-loaded chitosan-pullulan-silver-nanocomposite (CSPN) films …