[HTML][HTML] The chinchilla animal model for hearing science and noise-induced hearing loss

M Trevino, E Lobarinas, AC Maulden… - The Journal of the …, 2019 - pubs.aip.org
The chinchilla animal model for noise-induced hearing loss has an extensive history
spanning more than 50 years. Many behavioral, anatomical, and physiological …

Otitis media: recent advances in otitis media vaccine development and model systems

A Zahid, JC Wilson, ID Grice, IR Peak - Frontiers in Microbiology, 2024 - frontiersin.org
Otitis media is an inflammatory disorder of the middle ear caused by airways-associated
bacterial or viral infections. It is one of the most common childhood infections as globally …

Earhealth: an earphone-based acoustic otoscope for detection of multiple ear diseases in daily life

Y Jin, Y Gao, X Guo, J Wen, Z Li, Z Jin - Proceedings of the 20th annual …, 2022 - dl.acm.org
With the aging of the population and the long-time wearing of earphones, hearing health has
gradually emerged as a worldwide health issue. Early detection of hearing health conditions …

Panel 2: anatomy (eustachian tube, middle ear, and mastoid—anatomy, physiology, pathophysiology, and pathogenesis)

CM Alper, M Luntz, H Takahashi… - … –Head and Neck …, 2017 - journals.sagepub.com
Objective In this report, we review the recent literature (ie, past 4 years) to identify advances
in our understanding of the middle ear–mastoid–eustachian tube system. We use this review …

[HTML][HTML] Animal models of acute otitis media–a review with practical implications for laboratory research

NH Davidoss, YK Varsak, PL Santa Maria - European Annals of …, 2018 - Elsevier
Considerable animal research has focused on developing new strategies for the prevention
and treatment of acute otitis media (AOM). Several experimental models of AOM have thus …

3D finite element model of the chinchilla ear for characterizing middle ear functions

X Wang, RZ Gan - Biomechanics and modeling in mechanobiology, 2016 - Springer
Chinchilla is a commonly used animal model for research of sound transmission through the
ear. Experimental measurements of the middle ear transfer function in chinchillas have …

[HTML][HTML] Chronic otitis media is initiated by a bulla cavitation defect in the FBXO11 mouse model

J Del-Pozo, N MacIntyre, A Azar… - Disease Models & …, 2019 - journals.biologists.com
Auditory bulla cavitation defects are a cause of otitis media, but the normal cellular pattern of
bulla mesenchyme regression and its failure are not well understood. In mice, neural-crest …

Morphological changes in the round window membrane associated with Haemophilus influenzae-induced acute otitis media in the chinchilla

S Jiang, TW Seale, RZ Gan - International journal of pediatric …, 2016 - Elsevier
Objective The round window membrane (RWM) encloses the round window, the opening
into the scala tympani (ST) from the middle ear. During the course of acute otitis media …

Dynamic properties of tympanic membrane in a chinchilla otitis media model measured with acoustic loading

Z Yokell, X Wang, RZ Gan - Journal of …, 2015 - asmedigitalcollection.asme.org
Otitis media is the most common infectious disease in young children, which results in
changes in the thickness and mechanical properties of the tympanic membrane (TM) and …

Surface motion of tympanic membrane in a chinchilla model of acute otitis media

X Wang, RZ Gan - Journal of the Association for Research in …, 2018 - Springer
The conductive hearing loss caused by acute otitis media (AOM) is commonly related to a
reduction of the tympanic membrane (TM) mobility in response to sound stimuli. However …