The bubbling community of microorganisms, consisting of diverse colonies encased in a self-
produced protective matrix and playing an essential role in the persistence of infection and …

Acne vulgaris, a common and chronic disorder of the pilosebaceous unit, affects up to 85%
of adolescent and young adults. While a lot is already known about acne and its treatment …

Studies of the human skin microbiome suggest that Propionibacterium acnes strains may
contribute differently to skin health and disease. However, the immune phenotype and …

Acne is a common, chronic inflammatory condition affecting millions of people worldwide,
with significant negative impact on quality of life and mental health. Acne is characterized by …

Commensal or pathogenic bacterial communities of the skin interact with the host immune
system to preserve homeostasis or sustain disease. In this issue of the JCI, Agak et al …

Acne is a chronic inflammatory skin disease that primarily affects adolescents and is
attributed to various factors, including hormonal changes, genetic predisposition, and …

Antibiotic resistance is a major danger to public health that threatens to claim the lives of
millions of people per year within the next few decades. Years of necessary administration …

Antibiotic resistance in acne was first observed in the 1970s, and since the 1980s has
become a major concern in dermatologic daily practice. The mechanisms for this type of …

We design hybrid antibiotic peptide conjugates that can permeate membranes. Integration of
multiple components with different functions into a single molecule is often problematic, due …

Abstract Background Cationic antibacterial peptides (CAPs) and synthetic molecules
mimicking the amphiphilic structure of CAPs, such as ceragenins, are promising compounds …