Use of the CatWalk gait analysis system to assess functional recovery in rodent models of peripheral nerve injury–a systematic review

J Heinzel, G Längle, V Oberhauser, T Hausner… - Journal of Neuroscience …, 2020 - Elsevier
Injuries of the peripheral nervous system are common among the population affecting
around 3% of all trauma patients. This high clinical need in the field of peripheral nerve …

Review of piezoelectrical materials potentially useful for peripheral nerve repair

D Casal, MH Casimiro, LM Ferreira, JP Leal… - Biomedicines, 2023 - mdpi.com
It has increasingly been recognized that electrical currents play a pivotal role in cell
migration and tissue repair, in a process named “galvanotaxis”. In this review, we summarize …

Evaluation of functional recovery in rats after median nerve resection and autograft repair using computerized gait analysis

JC Heinzel, V Oberhauser, C Keibl… - Frontiers in …, 2021 - frontiersin.org
Computerized gait analysis is a common evaluation method in rat models of hind limb nerve
injuries, but its use remains unpublished in models of segmental nerve injury of the forelimb …

The median nerve injury model in pre-clinical research–a critical review on benefits and limitations

G Ronchi, M Morano, F Fregnan, P Pugliese… - Frontiers in Cellular …, 2019 - frontiersin.org
The successful introduction of innovative treatment strategies into clinical practise strongly
depends on the availability of effective experimental models and their reliable pre-clinical …

Exploring the neuroregenerative potential of tacrolimus

TM Saffari, M Bedar, JM Zuidam, AY Shin… - Expert review of …, 2019 - Taylor & Francis
Introduction: The clinical use of tacrolimus is characterized by many side effects which
include neurotoxicity. In contrast, tacrolimus has also shown to have neuroregenerative …

Chitin scaffold combined with autologous small nerve repairs sciatic nerve defects

B Wang, CF Lu, ZY Liu, S Han, P Wei… - Neural Regeneration …, 2022 - journals.lww.com
Although autologous nerve transplantation is the gold standard for treating peripheral nerve
defects, it has many clinical limitations. As an alternative, various tissue-engineered nerve …

Appropriate animal models for translational nerve research

K Haastert-Talini - Peripheral Nerve Tissue Engineering and …, 2022 - Springer
This chapter will focus on aspects to be considered when evaluating the properties of novel
materials and constructs for bioartificial and tissue-engineered nerve graft repair in …

Functional and physiological methods of evaluating median nerve regeneration in the rat

D Casal, E Mota-Silva, I Iria, D Pais, A Farinho… - JoVE (Journal of …, 2020 - jove.com
The main goal of this investigation is to show how to create and repair different types of
median nerve (MN) lesions in the rat. Moreover, different methods of simulating …

ESWT Diminishes Axonal Regeneration following Repair of the Rat Median Nerve with Muscle-In-Vein Conduits but Not after Autologous Nerve Grafting

JC Heinzel, V Oberhauser, C Keibl, B Schädl… - Biomedicines, 2022 - mdpi.com
Investigations reporting positive effects of extracorporeal shockwave therapy (ESWT) on
nerve regeneration are limited to the rat sciatic nerve model. The effects of ESWT on muscle …

Multimodular Bio-Inspired Organized Structures Guiding Long-Distance Axonal Regeneration

LR Doblado, C Martínez-Ramos, MM Pradas - Biomedicines, 2022 - mdpi.com
Axonal bundles or axonal tracts have an aligned and unidirectional architecture present in
many neural structures with different lengths. When peripheral nerve injury (PNI), spinal cord …