Small-ring heterocycles have found many applications both as useful starting materials in
the synthesis of more elaborate structures and as valuable targets of synthesis. Our review …

Organocatalytic Asymmetric Epoxidation and Aziridination of Olefins and Their Synthetic
Applications | Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In …

At last count, nearly 5000 halogenated natural products have been discovered. In
approximately half of these compounds, the carbon atom to which the halogen is bound is …

Bromination reactions have been made a lot more convenient since the invention of N-
bromoamide reagents. These reagents are more easily handled when compared to …

The structural features of polycyclic polyether natural products can, in some cases, be traced
to their biosynthetic origin. However in case that are less well understood, only biosynthetic …

The trans-fused polycyclic ethers are one of the most characteristic and spectacular classes
of compounds isolated from marine sources. These molecules are produced by marine …

The unprecedented structure of the marine natural product brevetoxin B was elucidated by
the research group of Nakanishi and Clardy in 1981. The ladderlike molecular architecture …

A unique procedure to effect a ring-expanding bromoetherification process is described,
wherein tetrahydrofurans and tetrahydropyrans are smoothly transformed into 8-and 9 …

Herein, we report the first total synthesis of marine ladder polyether gymnocin B (1) based
on a two-phase strategy. In Phase I, inspired by the proposed biosynthesis, epoxide …

In the first total synthesis of ent-dioxepandehydrothyrsiferol, the signature trans-anti-trans 7,
7, 6-fused tricyclic polyether framework was constructed in a single bromonium-initiated …