Successful solid organ transplantation reflects meticulous attention to the details of
immunosuppression, balancing risks for graft rejection against risks for infection. The “net …

New reliable biomarkers are needed to improve individual risk assessment for post‐
transplant infection, acute graft rejection and other immune‐related complications after solid …

Background Late antibody-mediated rejection (ABMR) is a leading cause of transplant
failure. Blocking IL-6 has been proposed as a promising therapeutic strategy. Methods We …

Kidney transplantation has become a routine procedure in the treatment of patients with
kidney failure, and requires collaboration of experts from different disciplines, such as …

Potent immunosuppressive drugs have been introduced into clinical care for solid organ
transplant recipients. It is now time to guide these drugs on an individual level to optimize …

Balancing immunosuppression to prevent rejection in solid organ transplant (SOT)
recipients remains challenging. Torque teno virus (TTV), a commensal non‐pathogenic …

The nonpathogenic and ubiquitous torque teno virus (TTV) is associated with
immunosuppression in solid organ transplant recipients. Studies in kidney transplant …

Background Drug-induced immunosuppression following kidney transplantation is crucial to
prevent allograft rejection, but increases risk for infectious disease. Tailoring of drug dosing …

Background Immunosuppression after kidney transplantation is mainly guided via plasma
tacrolimus trough level, which cannot sufficiently predict allograft rejection and infection. The …

Solid organ transplantation (SOT) recipients receive immunosuppressive therapy to avoid
rejection of the transplanted organ. Immunosuppressive therapy increases the risk of …