A molecular understanding of high-density lipoprotein (HDL) will allow a more complete
grasp of its interactions with key plasma remodelling factors and with cell-surface proteins …

Over the years, the relationship between high-density lipoprotein (HDL) and atherosclerosis,
initially highlighted by the Framingham study, has been revealed to be extremely complex …

Both alterations of lipid/lipoprotein metabolism and inflammatory events contribute to the
formation of the atherosclerotic plaque, characterized by the accumulation of abnormal …

Abstract Sphingosine-1-phosphate (S1P) has gained special attention in the high-density
lipoprotein (HDL) field because HDL is the most prominent plasma carrier of S1P and …

Although High Density Lipoprotein Cholesterol (HDL-C) levels are inversely proportional to
cardiovascular risk in many studies, recent pharmacological interventional studies with HDL …

The aim of this study was to correlate the lipid content and size of discoidal reconstituted
HDL particles with their ability to promote cellular cholesterol efflux. Homogeneous discoidal …

High-density lipoprotein (HDL) particles have experienced a turbulent decade of falling from
grace with widespread demotion from the most-sought-after therapeutic target to reverse …

Reverse cholesterol transport (RCT) is the pathway for removal of peripheral tissue
cholesterol and involves transport of cholesterol back to liver for excretion, starting from …

The dramatic failure of clinical trials evaluating the cholesterol ester transfer protein inhibitor
torcetrapib has led to considerable doubt about the value of raising high-density lipoprotein …

The lecithin: cholesterol acyltransferase (LCAT) enzyme is responsible for the synthesis of
cholesteryl esters in human plasma and plays a critical role in high density lipoprotein (HDL) …