Abstract Prolactin (PRL) is a 23-kDa protein hormone that binds to a single-span membrane
receptor, a member of the cytokine receptor superfamily, and exerts its action via several …

Estrogens are crucial determinants in the regulation of anterior pituitary function and
maintenance of tissue homeostasis. Estrogen actions in this gland are exerted through both …

RFamide-related peptides (RFRPs) regulate the release of various pituitary hormones in
vertebrates. It is completely unknown how the functions of RFRPs vary among animal …

Background Lactation insufficiency is a prevalent challenge for nursing mothers globally.
There is a growing interest in the use of herbal galactagogues for enhancing lactation, but …

Oestrogen powerfully affects the secretion of gonadotropin‐releasing hormone (GnRH) from
the brain in all species investigated, including sheep. Until recently, it was hypothesised that …

Estrogen (E) is a key regulator of the synthesis and secretion of pituitary reproductive
hormones [luteinizing hormone (LH), follicle-stimulating hormone (FSH) and prolactin …

Net estrogen sensitivity in target tissues critically depends on the regulated expression of full-
length and alternately processed estrogen receptor (ER) isoforms. However, the molecular …

Estradiol is a critical factor in the anterior pituitary secretory activity of mammalian females.
Previous reports have demonstrated the presence of oestrogen receptor alpha (ERα) and …

Postpartum estrogen (E2) withdrawal is known to be a particularly vulnerable time for
depressive symptoms. In this study, ovariectomized (OVX) mice were treated with co …

During late‐pregnancy, tuberoinfundibular dopaminergic (TIDA) neurones, a critical
component of the negative‐feedback loop regulating prolactin secretion, become …