Lipids are essential constituents of cellular membranes. Once regarded merely as structural
components, lipids have taken centre stage with the discovery of their roles in cell signalling …

In the almost 70 years since the first hints of its existence, the phosphoinositide,
phosphatidyl-D-myo-inositol 4, 5-bisphosphate has been found to be central in the …

Migrasomes, newly identified organelles, play crucial roles in intercellular communication,
contributing to organ development and angiogenesis. These vesicles, forming on retraction …

During the late phase of HIV type 1 (HIV-1) infection cycle, the virally encoded Gag
polyproteins are targeted to the inner leaflet of the plasma membrane (PM) for assembly …

By study of asymmetric membranes, models of the cell plasma membrane (PM) have
improved, with more realistic properties of the asymmetric lipid composition of the …

Many signal transductions resulting from ligand–receptor interactions occur at the cell
surface. These signaling pathways play essential roles in cell polarization, membrane …

Cells contain thousands of different lipids. Their rapid and redundant metabolism, dynamic
movement, and many interactions with other biomolecules have justly earned lipids a …

Phosphoinositides are amphipathic lipid molecules derived from phosphatidylinositol that
represent low abundance components of biological membranes. Rather than serving as …

Abstract Neurofibromatosis type 2 (NF2), which encodes merlin (moesin-ezrin-radixin-like
protein), belongs to the band 4.1, ezrin, radixin, moesin (FERM) domain-containing 4.1 …

Immunoreceptors have crucial roles in sensing environmental signals and initiating immune
responses to protect the host. Dysregulation of immunoreceptor signalling can therefore …