Functional brain imaging in humans has revealed task-specific increases in brain activity
that are associated with various mental activities. In the same studies, mysterious, task …

The structural and functional integrity of the brain depends on the delicate balance between
substrate delivery through blood flow and energy demands imposed by neural activity …

What is the nature of the vascular architecture in the cortex that allows the brain to meet the
energy demands of neuronal computations? We used high-throughput histology to …

▪ Abstract The development of functional magnetic resonance imaging (fMRI) has brought
together a broad community of scientists interested in measuring the neural basis of the …

The cerebral vascular system services the constant demand for energy during neuronal
activity in the brain. Attempts to delineate the logic of neurovascular coupling have been …

MRI was extended to the measurement of changes in oxidative metabolism in the normal
human during functionally induced changes in cellular activity. A noninvasive MRI method …

Because regional blood flow increases in association with the increased metabolic demand
generated by localised increases in neural activity, functional imaging researchers often …

Stroke is the world's second leading cause of mortality, with a high incidence of severe
morbidity in surviving victims. There are currently relatively few treatment options available …

Human MRI scanners at ultra-high magnetic field strengths of 7 T and higher are
increasingly available to the neuroscience community. A key advantage brought by ultra …

Cortical blood flow at the level of individual capillaries and the coupling of neuronal activity
to flow in capillaries are fundamental aspects of homeostasis in the normal and the diseased …