Lymphatic vessels in cancer

LC Dieterich, C Tacconi, L Ducoli… - Physiological …, 2022 - journals.physiology.org
The lymphatic system, composed of initial and collecting lymphatic vessels as well as lymph
nodes that are present in almost every tissue of the human body, acts as an essential …

Vascular endothelial growth factor signaling in development and disease

S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …

VEGF‐C is required for intestinal lymphatic vessel maintenance and lipid absorption

H Nurmi, P Saharinen, G Zarkada, W Zheng… - EMBO molecular …, 2015 - embopress.org
Vascular endothelial growth factor C (VEGF‐C) binding to its tyrosine kinase receptor
VEGFR‐3 drives lymphatic vessel growth during development and in pathological …

Regulation of VEGFR signalling in lymphatic vascular development and disease: an update

GA Secker, NL Harvey - International journal of molecular sciences, 2021 - mdpi.com
The importance of lymphatic vessels in a myriad of human diseases is rapidly gaining
recognition; lymphatic vessel dysfunction is a feature of disorders including congenital …

Lymphangiogenesis guidance by paracrine and pericellular factors

K Vaahtomeri, S Karaman, T Mäkinen… - Genes & …, 2017 - genesdev.cshlp.org
Lymphatic vessels are important for tissue fluid homeostasis, lipid absorption, and immune
cell trafficking and are involved in the pathogenesis of several human diseases. The …

VEGFR signaling during lymphatic vascular development: From progenitor cells to functional vessels

GA Secker, NL Harvey - Developmental Dynamics, 2015 - Wiley Online Library
Lymphatic vessels are an integral component of the cardiovascular system, serving
important roles in fluid homeostasis, lipid absorption, and immune cell trafficking. Defining …

Proteolytic cleavages in the VEGF family: generating diversity among angiogenic VEGFs, essential for the activation of lymphangiogenic VEGFs

J Künnapuu, H Bokharaie, M Jeltsch - Biology, 2021 - mdpi.com
Simple Summary Vascular endothelial growth factors (VEGFs) regulate the growth of blood
and lymphatic vessels. Some of them induce the growth of blood vessels, and others the …

Emerging roles for VEGF-D in human disease

SA Stacker, MG Achen - Biomolecules, 2018 - mdpi.com
Blood vessels and lymphatic vessels are located in many tissues and organs throughout the
body, and play important roles in a wide variety of prevalent diseases in humans. Vascular …

Hemostasis and anti-inflammatory abilities of AuNPs-coated chitosan dressing for burn wounds

JH Cherng, CAJ Lin, CC Liu, JZ Yeh, GY Fan… - Journal of Personalized …, 2022 - mdpi.com
Burn injuries are a common hazard in the military, as fire is likely to be weaponized. Thus, it
is important to find an effective substance to accelerate burn wound healing. This study used …

Vegfc/d-dependent regulation of the lymphatic vasculature during cardiac regeneration is influenced by injury context

CJ Vivien, C Pichol-Thievend, CB Sim… - Npj Regenerative …, 2019 - nature.com
The lymphatic vasculature mediates essential physiological functions including fluid
homeostasis, lipid and hormone transport, and immune cell trafficking. Recent studies have …