Adverse childhood experiences (ACEs) may be referred to by other terms (eg, early life adversity or stress and childhood trauma) and have a lifelong impact on mental and physical …
Major depressive disorder is a common psychiatric disorder associated with marked suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …
C Tsigos, I Kyrou, E Kassi, GP Chrousos - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Stress constitutes a state of threatened homeostasis triggered by intrinsic or extrinsic adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …
CS Carter - Frontiers in endocrinology, 2017 - frontiersin.org
Vasopressin (VP) and oxytocin (OT) are distinct molecules; these peptides and their receptors [OT receptor (OTR) and V1a receptor (V1aR)] also are evolved components of an …
A Menke - Current Neuropharmacology, 2024 - benthamdirect.com
Major depressive disorder (MDD) is a stress-related mental disorder with a lifetime prevalence of 20% and, thus, is one of the most prevalent mental health disorders …
S Sparapani, C Millet-Boureima, J Oliver, K Mu… - Biomedicines, 2021 - mdpi.com
Vasopressins are evolutionarily conserved peptide hormones. Mammalian vasopressin functions systemically as an antidiuretic and regulator of blood and cardiac flow essential for …
N Brandes, N Linial, M Linial - Scientific reports, 2021 - nature.com
The characterization of germline genetic variation affecting cancer risk, known as cancer predisposition, is fundamental to preventive and personalized medicine. Studies of genetic …
CC Kaufmann, A Ahmed, AL Burger, M Muthspiel… - Cells, 2022 - mdpi.com
Coronavirus disease-19 (COVID-19) emerged late December 2019 in the city of Wuhan, China and has since spread rapidly all over the world causing a global pandemic. While the …
NI Dmitrieva, M Boehm, PH Yancey… - Nature Reviews …, 2024 - nature.com
Body water balance is determined by fundamental homeostatic mechanisms that maintain stable volume, osmolality and the composition of extracellular and intracellular fluids. Water …