Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives

JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments

R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …

Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 …

S Del Prato, SE Kahn, I Pavo, GJ Weerakkody, Z Yang… - The Lancet, 2021 - thelancet.com
Background We aimed to assess efficacy and safety, with a special focus on cardiovascular
safety, of the novel dual GIP and GLP-1 receptor agonist tirzepatide versus insulin glargine …

[PDF][PDF] ISPAD Clinical Practice Consensus Guidelines 2022: Definition, epidemiology, and classification of diabetes in children and adolescents.

I Libman, A Haynes, S Lyons, P Pradeep… - Pediatric …, 2022 - digibete.org
This chapter serves as an update and replaces the 2018 ISPAD consensus guideline on
definition, epidemiology, and classification of diabetes in children and adolescents. 1 It …

A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives

J Reed, S Bain, V Kanamarlapudi - Diabetes, Metabolic Syndrome …, 2021 - Taylor & Francis
Abstract Type 2 diabetes (T2D), which has currently become a global pandemic, is a
metabolic disease largely characterised by impaired insulin secretion and action. Significant …

Management and prevention strategies for non-communicable diseases (NCDs) and their risk factors

A Budreviciute, S Damiati, DK Sabir, K Onder… - Frontiers in public …, 2020 - frontiersin.org
Non-communicable diseases (NCDs) are of increasing concern for society and national
governments, as well as globally due to their high mortality rate. The main risk factors of …

The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

JCN Chan, LL Lim, NJ Wareham, JE Shaw, TJ Orchard… - The Lancet, 2020 - thelancet.com
Executive summary 2020 will go down in history as the year when the global community was
awakened to the fragility of human health and the interdependence of the ecosystem …

[HTML][HTML] Type II diabetes mellitus: a review on recent drug based therapeutics

S Padhi, AK Nayak, A Behera - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder that occurs in the body because of decreased
insulin activity and/or insulin secretion. Pathological changes such as nephropathy …

[HTML][HTML] Gut microbiota: an important player in type 2 diabetes mellitus

Z Zhou, B Sun, D Yu, C Zhu - Frontiers in cellular and infection …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is one of the common metabolic diseases in the world. Due
to the rise in morbidity and mortality, it has become a global health problem. To date, T2DM …

Molecular mechanisms linking oxidative stress and diabetes mellitus

H Yaribeygi, T Sathyapalan, SL Atkin… - … medicine and cellular …, 2020 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …