Immune response, proliferation, migration and angiogenesis are juts a few of cellular events
that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have …

Snake venom contains a cocktail of compounds dominated by proteins and peptides, which
make up the toxin. The toxin components of snake venom attack several targets in the …

Animal venoms and their chemical compounds have aroused both empirical and scientific
attention for ages. However, there has been a significant increase in scientific investigations …

Despite advances in treating patients with melanoma, there are still many treatment
challenges to overcome. Studies with snake venom-derived proteins/peptides describe their …

Based on the high incidence and mortality rates of cancer, its therapy remains one of the
most vital challenges in the field of medicine. Consequently, enhancing the efficacy of …

Antimicrobial peptides are molecules synthetized by a large variety of organisms as an
innate defense against pathogens. These natural compounds have been identified as …

Latest advancement of omics technologies allows in-depth characterization of venom
compositions. In the present work we present a proteomic study of two snake venoms of the …

Animal-derived venom, like snake venom, has been proven to be valuable natural resources
for the drug development. Previously, snake venom was mainly investigated in its …

Antiangiogenic strategies are promising tools for cancer treatment and several other
disorders. In this sense, phospholipases A 2 (PLA 2 s) from snake venom have been …

Background Current immunotherapies with unexpected severe side effects and treatment
resistance have not resulted in the desired outcomes for patients with melanoma, and there …