A resurgence of interest and investment in the field of gene therapy, driven in large part by
advances in viral vector technology, has recently culminated in United States Food and Drug …

Lyophilization is a common, but cost-intensive, drying process to achieve protein
formulations with long-term stability. In the past, typical process optimization has focused on …

The freeze-drying process is a combination of 2 equally important processes, freezing, and
drying. In the past, the effort was mainly focused on optimizing the drying process without …

Solid-state is the preferred choice for storage of protein therapeutics to improve stability and
preserve the biological activity by decreasing the physical and chemical degradation …

Lyophilization has been used to improve the long-term stability of polymeric nanoparticles
for drug delivery applications, avoiding their instability in suspension. However, this …

Written by internationally recognized experts, Surimi and Surimi Seafood, Second Edition
provides a wealth of up-to-the-minute information on all aspects of the production of surimi …

Liquid formulations of vaccines are subject to instabilities that result from degradation
processes that proceed via a variety of physical and chemical pathways. In dried …

Biologic products encounter various types of interfacial stress during development,
manufacturing, and clinical administration. When proteins come in contact with vapor–liquid …

While entering a new century, lyophilization in the pharmaceutical field has been subjected
to ongoing development and steady expansion. This review aims to highlight recent …

Commercialization of protein‐based therapeutics is a challenging task in part due to the
difficulties in maintaining protein solutions safe and efficacious throughout the drug product …