Exotic mice as models for aging research: polemic and prospectus.
A comment on this article appears in" Exotic mice as models for aging research: polemic and
prospectus by R. Miller et al." Neurobiol Aging. 1999 Mar-Apr; 20 (2): 233-6; discussion 245 …
prospectus by R. Miller et al." Neurobiol Aging. 1999 Mar-Apr; 20 (2): 233-6; discussion 245 …
Big mice die young: early life body weight predicts longevity in genetically heterogeneous mice
Small body size has been associated with long life span in four stocks of mutant dwarf mice,
and in two varieties of dietary restriction in rodents. In this study, small body size at ages 2 …
and in two varieties of dietary restriction in rodents. In this study, small body size at ages 2 …
Biomarkers of aging: prediction of longevity by using age-sensitive T-cell subset determinations in a middle-aged, genetically heterogeneous mouse population
RA Miller - The Journals of Gerontology Series A: Biological …, 2001 - academic.oup.com
Seven T-cell subset values were measured in each of 559 mice at 8 months of age, and then
again in the 494 animals that reached 18 months of age. The group included virgin males …
again in the 494 animals that reached 18 months of age. The group included virgin males …
Mouse loci associated with life span exhibit sex-specific and epistatic effects
AU Jackson, AT Galecki, DT Burke… - The Journals of …, 2002 - academic.oup.com
We have looked for genetic predictors of life span in a sibship of mice created as a four-way
cross among inbred grandparental strains BALB/cJ, C57BL/6J, C3H/HeJ, and DBA/2J. To …
cross among inbred grandparental strains BALB/cJ, C57BL/6J, C3H/HeJ, and DBA/2J. To …
Announcement: four-way cross mouse stocks: a new, genetically heterogeneous resource for aging research
THE National Institue on Aging's (NIA) Animal Resources Office is the principal supplier of
standardized, specific pathogen free (SPF) rodents for research programs on the biology of …
standardized, specific pathogen free (SPF) rodents for research programs on the biology of …
T cell subset patterns that predict resistance to spontaneous lymphoma, mammary adenocarcinoma, and fibrosarcoma in mice
RA Miller, C Chrisp - The Journal of Immunology, 2002 - journals.aai.org
Aging leads to changes in the proportion of several T cell subsets in peripheral blood, but it
is not yet known whether these changes have prognostic significance for late-life diseases …
is not yet known whether these changes have prognostic significance for late-life diseases …
Coordinated genetic control of neoplastic and nonneoplastic diseases in mice
RA Miller, C Chrisp, AU Jackson… - The Journals of …, 2002 - academic.oup.com
Some models of aging imply that late-life diseases, though roughly synchronous, are the
result of distinct pathophysiological processes, each in turn influenced by polymorphisms at …
result of distinct pathophysiological processes, each in turn influenced by polymorphisms at …
Genetic polymorphisms in mouse genes regulating age-sensitive and age-stable T cell subsets
To see whether genetic polymorphisms regulate inter-individual differences in T cell subset
levels, we have conducted a genome scan in two populations of mice, bred as the progeny …
levels, we have conducted a genome scan in two populations of mice, bred as the progeny …
[PDF][PDF] Biochemical and genetic analyses of T cell aging in mice
RA Miller - 2002 - deepblue.lib.umich.edu
The aged immune system shows defects in cellular and humoral immune responses to
vaccines [37], infectious agents [7], and tumors [10], deficiencies whose root causes are not …
vaccines [37], infectious agents [7], and tumors [10], deficiencies whose root causes are not …