Moisturization and skin barrier function

AV Rawlings, CR Harding - Dermatologic therapy, 2004 - Wiley Online Library
Over the past decade, great progress has been made toward elucidating the structure and
function of the stratum corneum (SC), the outermost layer of the epidermis. SC cells …

Epidermal barrier dysfunction in atopic dermatitis

MJ Cork, S Danby, Y Vasilopoulos… - Textbook of Atopic …, 2008 - taylorfrancis.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with cutaneous
hyper-reactivity to environmental triggers that are innocuous to normal, non-atopic …

Rationale of drug encapsulation and release from biocompatible porous metal–organic frameworks

D Cunha, M Ben Yahia, S Hall, SR Miller… - Chemistry of …, 2013 - ACS Publications
A joint experimental and computational systematic exploration of the driving forces that
govern (i) encapsulation of active ingredients (solvent, starting material dehydration …

Natural skin surface pH is on average below 5, which is beneficial for its resident flora

H Lambers, S Piessens, A Bloem… - … journal of cosmetic …, 2006 - Wiley Online Library
Variable skin pH values are being reported in literature, all in the acidic range but with a
broad range from pH 4.0 to 7.0. In a multicentre study (N= 330), we have assessed the skin …

New perspectives on epidermal barrier dysfunction in atopic dermatitis: gene–environment interactions

MJ Cork, DA Robinson, Y Vasilopoulos… - Journal of Allergy and …, 2006 - Elsevier
Atopic dermatitis (AD) is a multifactorial, chronic inflammatory skin disorder in which genetic
mutations and cutaneous hyperreactivity to environmental stimuli play a causative role …

[HTML][HTML] Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7

C Caubet, N Jonca, M Brattsand, M Guerrin… - Journal of investigative …, 2004 - Elsevier
Corneodesmosin (CDSN), desmoglein 1 (DSG1), and desmocollin 1 (DSC1) are adhesive
proteins of the extracellular part of the corneodesmosomes, the junctional structures that …

The stratum corneum: structure and function in health and disease

CR Harding - Dermatologic therapy, 2004 - Wiley Online Library
Our understanding of the formation, structure, composition, and maturation of the stratum
corneum (SC) has progressed enormously over the past 30 years. Today, there is a growing …

Design, preparation, and characterization of effective dermal and transdermal lipid nanoparticles: a review

D Khater, H Nsairat, F Odeh, M Saleh, A Jaber… - Cosmetics, 2021 - mdpi.com
Limited permeability through the stratum corneum (SC) is a major obstacle for numerous
skin care products. One promising approach is to use lipid nanoparticles as they not only …

Skin physiology in men and women: in vivo evaluation of 300 people including TEWL, SC hydration, sebum content and skin surface pH

S Luebberding, N Krueger… - International journal of …, 2013 - Wiley Online Library
Objectives Evidence is given that differences in skin physiological properties exist between
men and women. However, despite an assessable number of available publications, the …

[HTML][HTML] Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle

AV Rawlings, PJ Matts - Journal of Investigative Dermatology, 2005 - Elsevier
'Stratum Corneum Moisturization At The Molecular Level'[1] was published over a decade
ago to review what was known about the biology of a common cosmetic problem called 'dry …