Advances in molecular diagnostics have enabled the identification of targetable driver
pathogenic variants, forming the basis of precision oncology care. However, the adoption of …

Abstract Purposeof Review Health disparities are preventable differences in the diagnosis,
treatment, and outcomes of many diseases, including central nervous system (CNS) tumors …

The Hispanic/Latinx population of the United States constitutes the second largest
racial/ethnic group in the nation, accounting for more than 60 million individuals according to …

Simple Summary There is conflicting evidence on the impact of TP53 co-mutations on
survival in patients with EGFR-mutated advanced non-small cell lung cancer (aNSCLC) …

PURPOSE Clinical trials of novel and targeted agents increasingly require biomarkers for
eligibility. Precision oncology continues to evolve, but challenges hamper broad use of …

Tumor genomic profiling (TGP) is used in oncology practice to optimize cancer treatment
and improve survival rates. However, TGP is underutilized among Black and African …

The advent of next-generation sequencing (NGS), including both tissue assays and
circulating tumor DNA (ct-DNA), has been pivotal in improving outcomes for patients with …

Simple Summary In this review article, we highlight the process and importance of
identifying neoantigens for immunotherapy for cancer. Although the process of identifying …

Comprehensive biomarker testing has become the standard of care for informing the choice
of the most appropriate targeted therapy for many patients with advanced cancer. Despite …

Importance Targeted therapies based on underlying tumor genomic susceptible alterations
have been approved for patients with metastatic prostate cancer (mPC) and advanced …