This is a review of the studies comparing unipolar and bipolar depression, with focus on the
course, symptomatology, neurobiology, and psychosocial literatures. These are reviewed …

The search for genes in bipolar disorder has provided numerous genetic loci that have been
linked to susceptibility to developing the disorder. However, because of the genetic …

Clinical studies over the past decades have attempted to uncover the biological factors
mediating the pathophysiology of bipolar disorder (BD) utilizing a variety of biochemical and …

Despite years of research into bipolar disorder (manic depression), its underlying
pathophysiology remains elusive. It is widely acknowledged that the disorder is strongly …

Emerging evidence from genome‐wide association studies (GWAS) support the association
of polymorphisms in the alpha 1C subunit of the L‐type voltage‐gated calcium channel gene …

Bipolar disorder (BD) is a major health problem. It causes significant morbidity and imposes
a burden on the society. Available treatments help a substantial proportion of patients but …

Objective: Self-mutilation has traditionally been associated with borderline personality
disorder, and seldom examined separately from suicide attempts. Clinical experience …

Over the past decade, the focus of research into the pathophysiology of mood disorders
(bipolar disorder and unipolar depression in particular) has shifted from an interest in the …

Bipolar disorder is a lifelong challenge--but it doesn't have to rule your life. Find the science-
based information you need in the revised third edition of this indispensable guide. Trusted …

There is increasing evidence that affective disorders are associated with dysfunction of
neurotransmitter postsynaptic transduction pathways and that chronic treatment with …