Pulsatility seems to have a teleological role because evolutionary hierarchy favors higher
ordered animals with more complex, multichamber circulatory systems that generate higher …

Rotary blood pumps (RBPs) operating at a constant speed generate non-physiologic blood
pressure and flow rate, which can cause endothelial dysfunction, leading to adverse clinical …

An ascending thoracic aortic aneurysm (ATAA) is a heterogeneous disease showing
different patterns of aortic dilatation and valve morphologies, each with distinct clinical …

Numerical simulations of cardiac blood pump systems are integral to the optimization of
device design, hydraulic performance and hemocompatibility. In wave membrane blood …

Atlas-based analyses of patients with cardiovascular diseases have recently been explored
to understand the mechanistic link between shape and pathophysiology. The construction of …

Transcatheter aortic valve implantation (TAVI) was initially developed for adult patients, but
there is a growing interest to expand this procedure to younger individuals with longer life …

Hemodynamics plays a crucial role in the growth of an abdominal aortic aneurysm (AAA)
and its possible rupture. Due to the serious consequences that arise from the aneurysm …

Transcatheter aortic valve replacement (TAVR) is increasingly being considered for use in
younger patients having longer life expectancy than those who were initially treated. The …

In ascending thoracic aortic aneurysms (ATAAs), aneurysm kinematics are driven by
ventricular traction occurring every heartbeat, increasing the stress level of dilated aortic …

Mitral valve regurgitation is a common heart valve disorder associated with significant
morbidity and mortality. Transcatheter mitral valve repair using the MitraClip device has …