Y Li, HY Yang, DS Lee - Journal of Controlled Release, 2021 - Elsevier
In situ-forming injectable hydrogels are smart biomaterials that can be implanted into living bodies with minimal invasion. Due to pioneer work of Prof. Sung Wan Kim in this field …
Hydrogels are composed of three-dimensional smart and/or hungry networks, which do not dissolve in water but swell considerably in an aqueous medium, demonstrating an …
Medicine relies on the use of pharmacologically active agents (drugs) to manage and treat disease. However, drugs are not inherently effective; the benefit of a drug is directly related …
Z Li, J Yang, XJ Loh - NPG Asia Materials, 2016 - nature.com
Polyhydroxyalkanoates (PHAs) comprise a group of natural biodegradable polyesters that are synthesized by microorganisms. However, several disadvantages limit their competition …
L Klouda - European Journal of Pharmaceutics and …, 2015 - Elsevier
Thermally responsive hydrogels modulate their gelation behavior upon temperature change. Aqueous solutions solidify into hydrogels when a critical temperature is reached. In …
Importantly, with the advent of hybridoma and recombinant DNA technologies, the limitations associated with the extraction and purification of pharmaceutical proteins from animal …
Thermoresponsive polymers have been investigated for a variety of clinical applications which make use of in situ gelation at physiological temperatures. However, for biomedical …
D Kai, SS Liow, XJ Loh - Materials Science and Engineering: C, 2014 - Elsevier
Electrospinning has received much attention recently due to the growing interest in nano- technologies and the unique material properties. This review focuses on recent progress in …
GQ Chen - Chemical society reviews, 2009 - pubs.rsc.org
Biopolyesters polyhydroxyalkanoates (PHA) produced by many bacteria have been investigated by microbiologists, molecular biologists, biochemists, chemical engineers …