Size-tunable strategies for a tumor targeted drug delivery system

W Yu, R Liu, Y Zhou, H Gao - ACS central science, 2020 - ACS Publications
Nanoparticles have been widely used in tumor targeted drug delivery, while the antitumor
effects are not always satisfactory due to the limited penetration and retention. As we all …

Advances in biodegradable and injectable hydrogels for biomedical applications

Y Li, HY Yang, DS Lee - Journal of Controlled Release, 2021 - Elsevier
In situ-forming injectable hydrogels are smart biomaterials that can be implanted into living
bodies with minimal invasion. Due to pioneer work of Prof. Sung Wan Kim in this field …

A mini review on hydrogels classification and recent developments in miscellaneous applications

K Varaprasad, GM Raghavendra, T Jayaramudu… - Materials Science and …, 2017 - Elsevier
Hydrogels are composed of three-dimensional smart and/or hungry networks, which do not
dissolve in water but swell considerably in an aqueous medium, demonstrating an …

Emerging frontiers in drug delivery

MW Tibbitt, JE Dahlman, R Langer - Journal of the American …, 2016 - ACS Publications
Medicine relies on the use of pharmacologically active agents (drugs) to manage and treat
disease. However, drugs are not inherently effective; the benefit of a drug is directly related …

Polyhydroxyalkanoates: opening doors for a sustainable future

Z Li, J Yang, XJ Loh - NPG Asia Materials, 2016 - nature.com
Polyhydroxyalkanoates (PHAs) comprise a group of natural biodegradable polyesters that
are synthesized by microorganisms. However, several disadvantages limit their competition …

Thermoresponsive hydrogels in biomedical applications: A seven-year update

L Klouda - European Journal of Pharmaceutics and …, 2015 - Elsevier
Thermally responsive hydrogels modulate their gelation behavior upon temperature change.
Aqueous solutions solidify into hydrogels when a critical temperature is reached. In …

Hydrogels for protein delivery

T Vermonden, R Censi, WE Hennink - Chemical reviews, 2012 - ACS Publications
Importantly, with the advent of hybridoma and recombinant DNA technologies, the limitations
associated with the extraction and purification of pharmaceutical proteins from animal …

Biodegradable thermoresponsive polymers: Applications in drug delivery and tissue engineering

KJ Hogan, AG Mikos - Polymer, 2020 - Elsevier
Thermoresponsive polymers have been investigated for a variety of clinical applications
which make use of in situ gelation at physiological temperatures. However, for biomedical …

Biodegradable polymers for electrospinning: Towards biomedical applications

D Kai, SS Liow, XJ Loh - Materials Science and Engineering: C, 2014 - Elsevier
Electrospinning has received much attention recently due to the growing interest in nano-
technologies and the unique material properties. This review focuses on recent progress in …

A microbial polyhydroxyalkanoates (PHA) based bio-and materials industry

GQ Chen - Chemical society reviews, 2009 - pubs.rsc.org
Biopolyesters polyhydroxyalkanoates (PHA) produced by many bacteria have been
investigated by microbiologists, molecular biologists, biochemists, chemical engineers …