The vertebrate control of locomotion involves all levels of the nervous system from cortex to
the spinal cord. Here, we aim to cover all main aspects of this complex behavior, from the …

Neuronal networks within the spinal cord directly control rhythmic movements of the
arms/forelimbs and legs/hindlimbs during locomotion in mammals. For an effective …

Most rehabilitation interventions after spinal cord injury (SCI) only target the sublesional
spinal networks, peripheral nerves, and muscles. However, mammalian locomotion is not a …

Body-weight supported locomotor training (BWST) promotes recovery of load-bearing
stepping in lower mammals, but its efficacy in individuals with a spinal cord injury (SCI) is …

Spinal cord injury is associated with chronic sensorimotor deficits due to the interruption of
ascending and descending tracts between the brain and spinal cord. Functional recovery …

Simple Summary The effects of mesenchymal stem cell (MSC) transplants on functional
recovery after spinal cord injury have been compared in humans and animal models. Data …

Mechanisms underlying spontaneous locomotor recovery after spinal cord injury (SCI)
remain unclear. Using adult zebrafish with complete SCI, we show that V2a interneurons …

After an incomplete spinal cord injury (SCI) spontaneous motor recovery can occur in
mammals, but the underlying neural substrates remain poorly understood. The motor cortex …

When the foot dorsum contacts an obstacle during locomotion, cutaneous afferents signal
central circuits to coordinate muscle activity in the four limbs. Spinal cord injury disrupts …

Amphibiousness in fishes spans the actinopterygian tree from the earliest to the most
recently derived species. The land environment requires locomotor force production different …