Circadian physiology of metabolism
S Panda - Science, 2016 - science.org
A majority of mammalian genes exhibit daily fluctuations in expression levels, making
circadian expression rhythms the largest known regulatory network in normal physiology …
circadian expression rhythms the largest known regulatory network in normal physiology …
The mammalian circadian timing system: organization and coordination of central and peripheral clocks
C Dibner, U Schibler, U Albrecht - Annual review of physiology, 2010 - annualreviews.org
Most physiology and behavior of mammalian organisms follow daily oscillations. These
rhythmic processes are governed by environmental cues (eg, fluctuations in light intensity …
rhythmic processes are governed by environmental cues (eg, fluctuations in light intensity …
Astrocytes regulate daily rhythms in the suprachiasmatic nucleus and behavior
Astrocytes are active partners in neural information processing [1, 2]. However, the roles of
astrocytes in regulating behavior remain unclear [3, 4]. Because astrocytes have persistent …
astrocytes in regulating behavior remain unclear [3, 4]. Because astrocytes have persistent …
Transplanted suprachiasmatic nucleus determines circadian period
The pacemaker role of the suprachiasmatic nucleus in a mammalian circadian system was
tested by neural transplantation by using a mutant strain of hamster that shows a short …
tested by neural transplantation by using a mutant strain of hamster that shows a short …
[HTML][HTML] Coordinated transcription of key pathways in the mouse by the circadian clock
In mammals, circadian control of physiology and behavior is driven by a master pacemaker
located in the suprachiasmatic nuclei (SCN) of the hypothalamus. We have used gene …
located in the suprachiasmatic nuclei (SCN) of the hypothalamus. We have used gene …
Persistence of circadian rhythmicity in a mammalian hypothalamic" island" containing the suprachiasmatic nucleus.
ST Inouye, H Kawamura - Proceedings of the National …, 1979 - National Acad Sciences
The experimental work described tested the prosposition that the suprachiasmatic nucleus
of the hypothalamus is an autonomous circadian pacemaker. Simultaneous recording from …
of the hypothalamus is an autonomous circadian pacemaker. Simultaneous recording from …
Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors
J Rutter, M Reick, LC Wu, SL McKnight - Science, 2001 - science.org
Clock: BMAL1 and NPAS2: BMAL1 are heterodimeric transcription factors that control gene
expression as a function of the light-dark cycle. Although built to fluctuate at or near a 24 …
expression as a function of the light-dark cycle. Although built to fluctuate at or near a 24 …
The suprachiasmatic nucleus: a 25-year retrospective
DR Weaver - Journal of biological rhythms, 1998 - journals.sagepub.com
The suprachiasmatic nuclei (SCN) of the anterior hypothalamus contain the master circadian
pacemaker in mammals. On the occasion of the 25th anniversary of the discovery of the …
pacemaker in mammals. On the occasion of the 25th anniversary of the discovery of the …
Regularization algorithms for learning that are equivalent to multilayer networks
Learning an input-output mapping from a set of examples, of the type that many neural
networks have been constructed to perform, can be regarded as synthesizing an …
networks have been constructed to perform, can be regarded as synthesizing an …
Circadian oscillation of a mammalian homologue of the Drosophila period gene
H Tei, H Okamura, Y Shigeyoshi, C Fukuhara… - Nature, 1997 - nature.com
Many biochemical, physiological and behavioural processes in organisms ranging from
microorganisms to vertebrates exhibit circadian rhythms. In Drosophila, the gene period …
microorganisms to vertebrates exhibit circadian rhythms. In Drosophila, the gene period …