Some individuals with a particular disease-causing mutation or genotype fail to express
most if not all features of the disease in question, a phenomenon that is known as 'reduced …

Familial Mediterranean fever (FMF) is a disease of early onset which can lead to significant
morbidity. In 2012, Single Hub and Access point for pediatric Rheumatology in Europe …

Summary Familial Mediterranean Fever (FMF) is the oldest and the most frequent of all
described hereditary periodic fever syndromes. The populations originating from …

Familial autoinflammatory diseases: genetics, pathogenesis a... : Current Opinion in
Rheumatology Familial autoinflammatory diseases: genetics, pathogenesis and treatment …

Abstract Objective Familial Mediterranean fever (FMF) has traditionally been considered an
autosomal‐recessive disease; however, it has been observed that a substantial number of …

Familial Mediterranean fever is inherited in an autosomal recessive manner. There are two
phenotypes: types 1 and 2. Familial Mediterranean fever type 1 is characterized by recurrent …

The innate immune system is the first line of defense against microorganisms and is
conserved in plants and animals. The nucleotide-binding domain, leucine rich containing …

Objective The clinical profile in familial Mediterranean fever (FMF), including its major
manifestation, amyloidosis, is influenced by MEFV allelic heterogeneity and other genetic …

OBJECTIVES: To identify the ethnic, clinical, genetic, and pharmacokinetic correlates of
colchicine treatment failure in patients with familial Mediterranean fever (FMF). METHODS …

Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease that is
prevalent in Mediterranean populations. While it is considered a rare disease in the rest of …