Background Primary failure of eruption (PFE) is a rare disease defined as incomplete tooth
eruption despite the presence of a clear eruption pathway. Orthodontic extrusion is not …

Tooth eruption is a unique biological process by which highly mineralized tissues emerge
into the outer world, and it occurs concomitantly with tooth root formation. These 2 processes …

Primary failure of eruption (PFE) is a rare disorder defined as incomplete tooth eruption
despite the presence of a clear eruption pathway. PFE is known to be caused by rare …

Here we describe AGCGA-quadruplexes, an unexpected addition to the well-known
tetrahelical families, G-quadruplexes and i-motifs, that have been a focus of intense …

Background Primary failure of eruption (PFE) is a hereditary condition, and linkage with
variants in the PTH1R gene has been demonstrated in many cases. The clinical severity and …

Tooth eruption is an important and unique biological process during craniofacial
development. Both the genetic and environmental factors can interfere with this process …

Objective: To test the hypothesis that mutations in the parathyroid hormone 1 receptor
(PTH1R) include effects in both primary and permanent teeth. Materials and Methods: DNA …

Parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) are two
peptides that regulate mineral ion homeostasis, skeletal development, and bone turnover by …

Every tissue is composed of multiple cell types that are developmentally, evolutionary and
functionally integrated into the unit we call an organ. Teeth, our organs for biting and …

Abstract Introduction Primary Failure of Eruption (PFE) is a rare condition affecting posterior
teeth eruption resulting in a posterior open bite malocclusion. Differential diagnosis like …