Respiratory tract infections are an important cause of morbidity and mortality worldwide.
Chief among these are infections involving the lower airways. The opportunistic bacterial …

Pathogenic bacteria cause various infections worldwide, especially in immunocompromised
and other susceptible individuals, and are also associated with high infant mortality rates in …

Sepsis is a clinical syndrome defined as a dysregulated host response to infection resulting
in life-threatening organ dysfunction. Sepsis is a major public health concern associated …

Autoimmunity is involved in the valvular damage caused by rheumatic heart disease (RHD).
Increased evidence has linked microRNAs (miRNAs/miRs) to autoimmune disease. Signal …

Micro-RNA (miR)-155 is a novel gene regulator with important roles in inflammation. Herein,
our study aimed to explore the role of miR-155 in LPS-induced acute lung injury (ALI). ALI in …

In recent years, IL-17A (IL-17), a pro-inflammatory cytokine, has received intense attention of
researchers and clinicians alike with documented effects in inflammation and autoimmune …

MicroRNAs (miRNAs) are short, conserved, non-coding RNA molecules that repress
translation, followed by the decay of miRNA-targeted mRNAs that encode molecules …

Cardiac dysfunction is correlated with detrimental prognosis of sepsis and contributes to a
high risk of mortality. After an initial hyperinflammatory reaction, most patients enter a …

Background MicroRNAs (miRNAs) are short, non-coding RNAs that regulate gene
expression at the post-transcriptional level and play a key role in the control of innate and …

Streptococcus pneumoniae (Spn) is a common respiratory pathogen and a frequent cause
of acute otitis media (AOM) in children. The first step in bacterial pathogenesis of AOM is the …