Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Galectins are a family of proteins that bind to specific glycans thereby deciphering the
information captured within the glycome. In the last two decades, several galectin family …

Objectives: The aim of this study was to examine the relation of galectin-3 (Gal-3), a marker
of cardiac fibrosis, with incident heart failure (HF) in the community. Background: Gal-3 is an …

Galectins, an ancient lectin family, are characterized by specific binding of β-galactosides
through evolutionary conserved sequence elements of carbohydrate-recognition domain …

Galectins are a family of soluble β‐galactoside‐binding lectins that play many important
regulatory roles in inflammation, immunity, and cancer. Recently, a role for galectin‐3 in the …

The liver is one of the major metabolic organs in the body, susceptible to injury caused by
various factors. In response to injury, sophisticated mechanisms are engaged to repair and …

Galectin‐3 is a β‐galactoside‐binding animal lectin of appro‐ximately 30 kDa and is
evolutionarily highly conserved. Galectin‐3 is promiscuous, its localization within the tissue …

The specific targeting of either tumor cells or immune cells in vivo by carefully designed and
appropriately surface-functionalized nanocarriers may become an effective therapeutic …

Central to fibrogenesis and the scarring of organs is the activation of fibroblasts into matrix-
secreting myofibroblasts. We demonstrate that Galectin-3 expression is up-regulated in …

Galectin-3 is a member of the galectin family, which consists of animal lectins that bind β-
galactosides. Recently, a role for galectin-3 in the pathophysiology of heart failure has been …