Intracellular cellobiose metabolism and its applications in lignocellulose-based biorefineries

V Parisutham, SP Chandran, A Mukhopadhyay… - Bioresource …, 2017 - Elsevier
Complete hydrolysis of cellulose has been a key characteristic of biomass technology
because of the limitation of industrial production hosts to use cellodextrin, the partial …

A GntR Family Transcription Factor in Streptococcus mutans Regulates Biofilm Formation and Expression of Multiple Sugar Transporter Genes

Z Li, Z Xiang, J Zeng, Y Li, J Li - Frontiers in microbiology, 2019 - frontiersin.org
GntR family transcription factors have been implicated in the regulation of carbohydrate
transport and metabolism in many bacteria. However, the function of this transcription factor …

It Takes Two to Tango: Combining Conventional Culture With Molecular Diagnostics Enhances Accuracy of Streptococcus pneumoniae Detection and Pneumococcal …

WR Miellet, J van Veldhuizen, D Litt… - Frontiers in …, 2022 - frontiersin.org
Background The specificity of molecular methods for the detection of Streptococcus
pneumoniae carriage is under debate. We propose a procedure for carriage surveillance …

Hemoglobin stimulates vigorous growth of Streptococcus pneumoniae and shapes the pathogen's global transcriptome

F Akhter, E Womack, JE Vidal, Y Le Breton… - Scientific Reports, 2020 - nature.com
Streptococcus pneumoniae (Spn) must acquire iron from the host to establish infection. We
examined the impact of hemoglobin, the largest iron reservoir in the body, on pneumococcal …

Characterization of an operon required for growth on cellobiose in Clostridioides difficile

MK Hasan, BA Dhungel, R Govind - Microbiology, 2021 - microbiologyresearch.org
Cellobiose metabolism is linked to the virulence properties in numerous bacterial
pathogens. Here, we characterized a putative cellobiose PTS operon of Clostridiodes …

LacR Is a Repressor of lacABCD and LacT Is an Activator of lacTFEG, Constituting the lac Gene Cluster in Streptococcus pneumoniae

M Afzal, S Shafeeq, OP Kuipers - Applied and environmental …, 2014 - Am Soc Microbiol
Comparison of the transcriptome of Streptococcus pneumoniae strain D39 grown in the
presence of either lactose or galactose with that of the strain grown in the presence of …

The challenges of using oropharyngeal samples to measure pneumococcal carriage in adults

LK Boelsen, EM Dunne, KA Gould, FT Ratu, JE Vidal… - Msphere, 2020 - Am Soc Microbiol
Streptococcus pneumoniae (the pneumococcus) carriage is commonly used to measure
effects of pneumococcal vaccines. Based on findings from culture-based studies, the World …

Identification of a Novel Small Non-Coding RNA Modulating the Intracellular Survival of Brucella melitensis

Y Wang, Y Ke, J Xu, L Wang, T Wang, H Liang… - Frontiers in …, 2015 - frontiersin.org
Bacterial small non-coding RNAs (sRNAs) are gene expression modulators respond to
environmental changes, stressful conditions, and pathogenesis. In this study, by using a …

Sialic Acid-Mediated Gene Expression in Streptococcus pneumoniae and Role of NanR as a Transcriptional Activator of the nan Gene Cluster

M Afzal, S Shafeeq, H Ahmed… - Applied and …, 2015 - Am Soc Microbiol
In this study, we investigated the transcriptomic response of Streptococcus pneumoniae D39
to sialic acid (N-acetylneuraminic acid [Neu5Ac]). Transcriptome comparison of wild-type …

UlaR activates expression of the ula operon in Streptococcus pneumoniae in the presence of ascorbic acid

M Afzal, S Shafeeq, B Henriques-Normark… - …, 2015 - microbiologyresearch.org
In this study, the regulatory mechanism of the ula (utilization of l-ascorbic acid) operon,
putatively responsible for transport and utilization of ascorbic acid in Streptococcus …