Mesenchymal stem cells and their small extracellular vesicles as crucial immunological efficacy for hepatic diseases

Y Tang, P Wu, L Li, W Xu, J Jiang - Frontiers in immunology, 2022 - frontiersin.org
Mesenchymal stem cell small extracellular vesicles (MSC-sEVs) are a priority for
researchers because of their role in tissue regeneration. sEVs act as paracrine factors and …

The role of mesenchymal stem cells in the occurrence, development, and therapy of hepatocellular carcinoma

X Zhang, N Li, Y Zhu, W Wen - Cancer Medicine, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common type of liver malignant tumor, with high
recurrence and mortality rates. Mesenchymal stem cells (MSCs) are multipotent cells that …

Combined inhibition of TGF-β1-induced EMT and PD-L1 silencing re-sensitizes hepatocellular carcinoma to sorafenib treatment

R Shrestha, P Prithviraj, KR Bridle… - Journal of Clinical …, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common type of primary hepatic malignancy.
HCC is one of the leading causes of cancer deaths worldwide. The oral multi-tyrosine kinase …

Sorafenib alleviates inflammatory signaling of tumor microenvironment in precancerous lung injuries

B Cicek, A Hacimuftuoglu, M Kuzucu, A Cetin, Y Yeni… - Pharmaceuticals, 2023 - mdpi.com
According to population-based studies, lung cancer is the prominent reason for cancer-
related mortality worldwide in males and is also rising in females at an alarming rate …

[HTML][HTML] Angiogenesis and its targeting in glioblastoma with focus on clinical approaches

F Daneshimehr, Z Barabadi, S Abdolahi… - Cell Journal …, 2022 - ncbi.nlm.nih.gov
Angiogenesis is a characteristic of glioblastoma (GBM), the most fatal and therapeutic-
resistant brain tumor. Highly expressed angiogenic cytokines and proliferated microvascular …

Role of immunotherapies and stem cell therapy in the management of liver cancer: A comprehensive review

FEM Ali, IM Ibrahim, HS Althagafy… - International …, 2024 - Elsevier
Liver cancer (LC) is the sixth most common disease and the third most common cause of
cancer-related mortality. The WHO predicts that more than 1 million deaths will occur from …

Hepatocellular carcinoma patients serum modulates the regenerative capacities of adipose mesenchymal stromal cells

RA Salah, AM El-Derby, Z El-Gammal, B Wadie… - Heliyon, 2024 - cell.com
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers causing the highest
mortality rate worldwide. Treatment options of surgery, radiation, cytotoxic drugs and liver …

Effects of mesenchymal stem cells versus curcumin on sonic hedgehog signaling in experimental model of Hepatocellular Carcinoma

MS Abdel-Tawab, H Fouad, AY Sedeak… - Molecular Biology …, 2024 - Springer
Abstract Background Sonic Hedgehog (SHH) is a fundamental signaling pathway that
controls tissue reconstruction, stem cell biology, and differentiation and has a role in gut …

Anti‐inflammatory effect of mesenchymal stem cells on hepatocellular carcinoma in the xenograft mice model

S Hajighasemlou, M Nikbakht, S Pakzad… - Veterinary Medicine …, 2022 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) is the fifth most diagnosed cancer and the
second leading cause of cancer‐related deaths worldwide. Sorafenib is the standard …

[HTML][HTML] Mesenchymal stem cells as professional actors in gastrointestinal cancer therapy: From Naïve to genetically modified

MN Sabet, MK Esfeh, N Nasrabadi… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Considering the high incidence and mortality rate of gastrointestinal cancers (GIs) worldwide
and partial success of the current available GI cancer treatments, there is a necessity to …