In the absence of contemporary, population-based epidemiological studies, estimates of the
incidence and prevalence of the inherited cardiomyopathies have been derived from …

Genetic diseases that affect the cardiovascular system are relatively common and include
cardiac channelopathies, cardiomyopathies, aortopathies, hypercholesterolemias, and …

Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited
disease characterized by ventricular arrhythmias and progressive ventricular dysfunction …

Arrhythmogenic cardiomyopathy (ACM) is a heritable cardiomyopathy characterized by
frequent ventricular arrhythmias and progressive ventricular dysfunction. Risk of sudden …

The role that mechanical forces play in shaping the structure and function of the heart is
critical to understanding heart formation and the etiology of disease but is challenging to …

Background: There is a paucity of data regarding the phenotype of dilated cardiomyopathy
(DCM) gene variants in the general population. We aimed to determine the frequency and …

Background: Pathogenic and likely pathogenic variants associated with arrhythmogenic
right ventricular cardiomyopathy (ARVC), dilated cardiomyopathy (DCM), and hypertrophic …

Arrhythmogenic cardiomyopathy (ACM) is a life-threatening cardiac disease caused by
mutations in genes predominantly encoding for desmosomal proteins that lead to alterations …

Aims The population prevalence of cardiomyopathies and the natural history of symptomatic
heart failure (HF) and arrhythmia across cardiomyopathy phenotypes is poorly understood …

Introduction: DNA-based population screening has been proposed as a public health
solution to identify individuals at risk for serious health conditions who otherwise may not …