Remodelling of the tumour microenvironment by the kallikrein-related peptidases

S Srinivasan, T Kryza, J Batra, J Clements - Nature Reviews Cancer, 2022 - nature.com
Kallikrein-related peptidases (KLKs) are critical regulators of the tumour microenvironment.
KLKs are proteolytic enzymes regulating multiple functions of bioactive molecules including …

Prognostic impact of kallikrein‐related peptidase transcript levels in prostate cancer

TPK Lehto, RM Kovanen, S Lintula… - … Journal of Cancer, 2023 - Wiley Online Library
We aimed to study mRNA levels and prognostic impact of all 15 human kallikrein‐related
peptidases (KLK s) and their targets, proteinase‐activated receptors (PAR s), in surgically …

Regulatory potential of long non-coding rnas (LncRNAs) in boar spermatozoa with good and poor freezability

L Fraser, Ł Paukszto, A Mańkowska, P Brym, P Gilun… - Life, 2020 - mdpi.com
Long non-coding RNAs (lncRNAs) are suggested to play an important role in the sperm
biological processes. We performed de novo transcriptome assembly to characterize …

Kallikrein-related peptidases protein expression in lymphoid tissues suggests potential implications in immune response

PS Filippou, AH Ren, A Soosaipillai, R Safar… - Clinical …, 2020 - Elsevier
Abstract Objectives Kallikrein-related peptidases (KLKs) are a subgroup of 15 secreted
chymotrypsin-and trypsin-like serine proteases that have been reported to possess novel …

Role of Epigenetic Therapy in the Modulation of Tumor Growth and Migration in Human Castration-Resistant Prostate Cancer Cells with Neuroendocrine …

A Dicitore, MG Bacalini, D Saronni, G Gaudenzi… - …, 2022 - karger.com
Introduction: Neuroendocrine transdifferentiation (NED) of prostate cancer (PC) cells is
associated with the development of resistance to antiandrogen therapy and poor prognosis …

Prostat kanseri hücre modelinde IL-6 ve TNF-α'nın KLK4 geninin regülasyonu üzerine etkisi

S Onat - 2024 - search.proquest.com
Prostat kanseri dünya genelinde yüksek sıklıkla görünen bir kanser türü olarak yıllar boyu
tanı ve tedavisi için birçok araştırma yapılmaktadır. Kanserin gelişmesinde ve …