Cryopreservation of cells and biologics underpins all biomedical research from routine
sample storage to emerging cell-based therapies, as well as ensuring cell banks provide …

Significance: The imino acid proline is utilized by different organisms to offset cellular
imbalances caused by environmental stress. The wide use in nature of proline as a stress …

Insect performance is limited by the temperature of the environment, and in temperate, polar,
and alpine regions, the majority of insects must face the challenge of exposure to low …

Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …

Insects have evolved a number of physiological mechanisms for coping with the detrimental
effects of low temperature. As autumn progresses, insects use environmental signals such …

Freeze tolerance–the ability to survive internal ice formation–has evolved repeatedly in
insects, facilitating survival in environments with low temperatures and/or high risk of …

Cold tolerance is a key determinant of insect distribution and abundance, and thermal
acclimation can strongly influence organismal stress tolerance phenotypes, particularly in …

Gut symbiotic bacteria have a substantial impact on host physiology and ecology. However,
the contribution of gut microbes to host fitness during long-term low-temperature stress is still …

Drosophila suzukii Matsumura, often called spotted wing drosophila, is an exotic vinegar fly
that is native to Southeast Asia and was first detected in the continental United States in …

Ice-binding proteins (IBPs) from extremophile organisms can modulate ice formation and
growth. There are many (bio) technological applications of IBPs, from cryopreservation to …