The formulation of medicines for children remains a challenge. An ideal pediatric formulation
must allow accurate dose administration and be in a dosage form that can be handled by the …

Background Early termination of prolonged seizures with intravenous administration of
benzodiazepines improves outcomes. For faster and more reliable administration …

Antiepileptic drugs are commonly given orally for chronic treatment of epilepsy. The
treatment of epilepsy requires administration of medications for both acute and chronic …

Background Kainic acid (KA)-induced status epilepticus (SE) was involved with release of
free radicals. Sesamin is a well-known antioxidant from sesame seeds and it scavenges free …

Since the approval of chlordiazepoxide in 1960 by the United States Food and Drug
Administration (FDA), benzodiazepines have been widely utilized, including in the practice …

This study aimed to identify and map available evidence relating to patient safety when
using ambulance services. There was inconsistency of information on attitudes and …

Since its introduction in 2006, 43 patients with various forms of status epilepticus (SE) have
been treated with the intravenous formulation of levetiracetam (LEV) in our clinic. After …

Background Neurological emergencies are one of the major diagnosis groups in the
Emergency Medical Services (EMS) with the highest rate of misdiagnosis. Despite the …

Objective Acute seizure attack is a stressful experience both for health care personnel and
parents. These attacks might cause morbidity and mortality among patients, so reliable …

Status epilepticus is an emergency condition in patients with prolonged seizure or recurrent
seizures without full recovery between them. The pathophysiological mechanisms of status …