Immune activation in irritable bowel syndrome: what is the evidence?

J Aguilera-Lizarraga, H Hussein… - Nature Reviews …, 2022 - nature.com
Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder that is
characterized by abdominal pain and an altered defecation pattern. It affects between 5 and …

Therapeutic effect of baicalin on inflammatory bowel disease: A review

X Wang, L Xie, J Long, K Liu, J Lu, Y Liang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Baicalin (BI) is an important biologically active flavonoid
isolated from the root of Scutellaria radix (Huang Qin). Traditionally Scutellaria radix was the …

[HTML][HTML] Supplementation of lactic acid bacteria has positive effects on the mucosal health of Atlantic salmon (Salmo salar) fed soybean meal

N Nimalan, SL Sørensen, A Fečkaninová, J Koščová… - Aquaculture …, 2023 - Elsevier
We investigated the ability of lactic acid bacteria, when added individually or in combination
in feeds, to prevent soybean meal-induced enteritis in Atlantic salmon. A control diet …

The functional role of lactoferrin in intestine mucosal immune system and inflammatory bowel disease

N Liu, G Feng, X Zhang, Q Hu, S Sun, J Sun… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's
disease (CD), is one of the main types of intestinal inflammatory diseases with intestine …

Aqueous extract of Paeoniae Radix Alba (Paeonia lactiflora Pall.) ameliorates DSS-induced colitis in mice by tunning the intestinal physical barrier, immune …

BF Yan, X Chen, YF Chen, SJ Liu, CX Xu… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Ulcerative colitis (UC) is a chronic non-specific intestinal
inflammatory disease, the pathogenesis of which is strongly associated with the …

The intestine: A highly dynamic microenvironment for IgA plasma cells

K Pracht, J Wittner, F Kagerer, HM Jäck… - Frontiers in …, 2023 - frontiersin.org
To achieve longevity, IgA plasma cells require a sophisticated anatomical microenvironment
that provides cytokines, cell-cell contacts, and nutrients as well as metabolites. The intestinal …

Contribution of gut-derived T cells to extraintestinal autoimmune diseases

Q Wang, Y Wu, Q Lu, M Zhao - Trends in Immunology, 2024 - cell.com
The mammalian intestine harbors abundant T cells with high motility, where these cells can
affect both intestinal and extraintestinal disorders. Growing evidence shows that gut-derived …

The intestinal immune system and gut barrier function in obesity and ageing

SJ Shemtov, R Emani, O Bielska… - The FEBS …, 2023 - Wiley Online Library
Obesity and ageing predispose to numerous, yet overlapping chronic diseases. For
example, metabolic abnormalities, including insulin resistance (IR) and type 2 diabetes …

Gut immune microenvironment and autoimmunity

Q Wang, Q Lu, S Jia, M Zhao - International Immunopharmacology, 2023 - Elsevier
A variety of immune cells or tissues are present in the gut to form the gut immune
microenvironment by interacting with gut microbiota, and to maintain the gut immune …

Intestinal factors promoting the development of RORγt+ cells and oral tolerance

R López-Fandiño, E Molina… - Frontiers in …, 2023 - frontiersin.org
The gastrointestinal tract has to harmonize the two seemingly opposite functions of fulfilling
nutritional needs and avoiding the entry of pathogens, toxins and agents that can cause …