Reduced susceptibility and increased resistance of bacteria against disinfectants: A systematic review

U Rozman, M Pušnik, S Kmetec, D Duh, S Šostar Turk - Microorganisms, 2021 - mdpi.com
Disinfectants are used to reduce the concentration of pathogenic microorganisms to a safe
level and help to prevent the transmission of infectious diseases. However, bacteria have a …

[HTML][HTML] A review of Spaulding's classification system for effective cleaning, disinfection and sterilization of reusable medical devices: Viewed through a modern-day …

NJ Rowan, T Kremer, G McDonnell - Science of the Total Environment, 2023 - Elsevier
Despite advances in medicine and innovations in many underpinning fields including
disease prevention and control, the Spaulding classification system, originally proposed in …

Interference with quorum-sensing signal biosynthesis as a promising therapeutic strategy against multidrug-resistant pathogens

O Fleitas Martínez, PO Rigueiras, AS Pires… - Frontiers in cellular …, 2019 - frontiersin.org
Faced with the global health threat of increasing resistance to antibiotics, researchers are
exploring interventions that target bacterial virulence factors. Quorum sensing is a …

Prevalence of resistance genes to biocides in antibiotic-resistant Pseudomonas aeruginosa clinical isolates

M Namaki, S Habibzadeh, H Vaez, M Arzanlou… - Molecular Biology …, 2022 - Springer
Background Biocides are frequently used as preservative, disinfectant and sterilizer against
many microorganisms in hospitals, industry and home. However, the reduced susceptibility …

Combined hemicellulolytic and phenoloxidase activities of Thermobacillus xylanilyticus enable growth on lignin-rich substrates and the release of phenolic molecules

Q Czerwiec, B Chabbert, D Crônier, B Kurek… - Bioresource …, 2024 - Elsevier
Major challenge in biorefineries is the use of all lignocellulosic components, particularly
lignins. In this study, Thermobacillus xylanilyliticus grew on kraft lignin, steam-exploded and …

Core and accessory genomic traits of Vibrio cholerae O1 drive lineage transmission and disease severity

A Maciel-Guerra, K Babaarslan, M Baker… - Nature …, 2024 - nature.com
Abstract In Bangladesh, Vibrio cholerae lineages are undergoing genomic evolution, with
increased virulence and spreading ability. However, our understanding of the genomic …

One Step Forward with Dry Surface Biofilm (DSB) of Staphylococcus aureus: TMT-Based Quantitative Proteomic Analysis Reveals Proteomic Shifts between DSB and …

MA Rahman, A Amirkhani, F Parvin… - International Journal of …, 2022 - mdpi.com
The Gram-positive bacterium Staphylococcus aureus is responsible for serious acute and
chronic infections worldwide and is well-known for its biofilm formation ability. Recent …

[HTML][HTML] A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens

P Vella, RS Rudraraju, T Lundbäck, H Axelsson… - Bioorganic & Medicinal …, 2021 - Elsevier
The spread of antibiotic resistance within the ESKAPE group of human pathogenic bacteria
poses severe challenges in the treatment of infections and maintenance of safe hospital …

Overcoming barriers to medium-chain fatty alcohol production

Y Su, AM Mangus, WT Cordell, BF Pfleger - Current Opinion in …, 2024 - Elsevier
Highlights•mc FaOHs are valuable oleochemicals that demand development of a
sustainable source..•Substrate selectivity and product toxicity hinder microbial mc FaOH …

Synthesis and evaluation of phenylimidazole FabK inhibitors as new Anti-C. Difficile agents

K Norseeda, FBA Pavel, JT Rutherford, HN Meer… - Bioorganic & medicinal …, 2023 - Elsevier
Abstract Previously, 1-((4-(4-bromophenyl)-1H-imidazol-2-yl) methyl)-3-(5-(pyridin-2-ylthio)
thiazol-2-yl) urea bearing a p-bromine substitution was shown to possess selective inhibitory …