Electrochemistry has recently gained increased attention as a versatile strategy for
achieving challenging transformations at the forefront of synthetic organic chemistry …

Over the past decade, the landscape of molecular synthesis has gained major impetus by
the introduction of late-stage functionalization (LSF) methodologies. C–H functionalization …

Since the definition of the “12 Principles of Green Chemistry” more than 20 years ago,
chemists have become increasingly mindful of the need to conserve natural resources and …

C–H functionalization reactions are playing an increasing role in the preparation and
modification of complex organic molecules, including pharmaceuticals, agrochemicals and …

The direct functionalization of C (sp3)–H bonds represents one of the most investigated
approaches to develop new synthetic methodology. Among the available strategies for …

Polystyrene upcycling to valuable commodity feedstocks is essential for reducing plastic
waste. Photooxidative degradation has emerged as a method for converting polystyrene to …

The selective and efficient C–H methylation of sp2 and sp3 carbon centres has become a
powerful transformation in the synthetic toolbox. Due to the potential for profound changes to …

A visible-light-promoted photoredox/nickel protocol for the enantioselective three-
component carboarylation of alkenes with tertiary and secondary alkyltrifluoroborates and …

Radical reactivity is a powerful tool for molecular construction that often provides bond-
forming strategies and retrosynthetic disconnections complementary to those available …

Recognizing Nature's unique ability to perform challenging oxygenation reactions with
exquisite selectivity parameters at iron-dependent oxygenases, chemists have long sought …