Adult neurogenesis in the hippocampus is a notable process due not only to its uniqueness
and potential impact on cognition but also to its localized vertical integration of different …

With potential relevance for brain-mapping work, hydrogel-based structures can now be built
from within biological tissue to allow subsequent removal of lipids without mechanical …

Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

Perceptual constancy requires the brain to maintain a stable representation of sensory input.
In the olfactory system, activity in primary olfactory cortex (piriform cortex) is thought to …

Episodic memories initially require rapid synaptic plasticity within the hippocampus for their
formation and are gradually consolidated in neocortical networks for permanent storage …

Deciphering how neural circuits are anatomically organized with regard to input and output
is instrumental in understanding how the brain processes information. For example, locus …

The brain's response to sensory input is strikingly modulated by behavioral state. Notably,
the visual response of mouse primary visual cortex (V1) is enhanced by locomotion, a …

The central processing pathways of the human olfactory system are not fully understood.
The olfactory bulb projects directly to a number of cortical brain structures, but the distinct …

In most sensory modalities, neuronal connectivity reflects behaviorally relevant stimulus
features, such as spatial location, orientation, and sound frequency. By contrast, the …

Obtaining high-resolution information from a complex system, while maintaining the global
perspective needed to understand system function, represents a key challenge in biology …